[HTML][HTML] Germline modification of domestic animals

L Tang, R González, I Dobrinski - Animal reproduction/Colegio …, 2015 - ncbi.nlm.nih.gov
Genetically-modified domestic animal models are of increasing significance in biomedical
research and agriculture. As authentic ES cells derived from domestic animals are not yet …

Insights on bovine genetic engineering and cloning

FF Bressan, JR Sangalli, LVF Pessôa… - Pesquisa Veterinária …, 2013 - SciELO Brasil
Transgenic technology has become an essential tool for the development of animal
biotechnologies, and animal cloning through somatic cell nuclear transfer (SCNT) enabled …

[PDF][PDF] Generation of transgenic livestock by somatic cell nuclear transfer

P Bosch, CA Hodges, SL Stice - Biotecnología Aplicada, 2004 - biblat.unam.mx
The ability to produce transgenic animals through the introduction of exogenous DNA has
existed for many years. However, past methods available to generate transgenic animals …

25th ANNIVERSARY OF CLONING BY SOMATIC CELL NUCLEAR TRANSFER: Generation of genetically engineered livestock using somatic cell nuclear transfer

IA Polejaeva - Reproduction, 2021 - rep.bioscientifica.com
Genetic engineering (GE) of livestock initially has been accomplished primarily using
pronuclear microinjection into zygotes (1985–1996). The applications of the technology …

Generation of bovine transgenics using somatic cell nuclear transfer

CA Hodges, SL Stice - Reproductive Biology and Endocrinology, 2003 - Springer
The ability to produce transgenic animals through the introduction of exogenous DNA has
existed for many years. However, past methods available to generate transgenic animals …

Somatic cell nuclear transfer and transgenesis in large animals: current and future insights

C Galli, I Lagutina, A Perota, S Colleoni… - … in domestic animals, 2012 - Wiley Online Library
Contents Somatic cell nuclear transfer (SCNT) was first developed in livestock for the
purpose of accelerating the widespread use of superior genotypes. Although many …

Targeted gene editing in porcine spermatogonia

D Webster, A Bondareva, S Solin, T Goldsmith… - Frontiers in …, 2021 - frontiersin.org
To study the pathophysiology of human diseases, develop innovative treatments, and refine
approaches for regenerative medicine require appropriate preclinical models. Pigs share …

Artificial cloning of domestic animals

CL Keefer - Proceedings of the National Academy of …, 2015 - National Acad Sciences
Domestic animals can be cloned using techniques such as embryo splitting and nuclear
transfer to produce genetically identical individuals. Although embryo splitting is limited to …

Current progress of genome editing in livestock

K Lee, K Uh, K Farrell - Theriogenology, 2020 - Elsevier
Historically, genetic engineering in livestock proved to be challenging. Without stable
embryonic stem cell lines to utilize, somatic cell nuclear transfer (SCNT) had to be employed …

Advancements in somatic cell nuclear transfer and future perspectives

K Lee, RS Prather - Animal Frontiers, 2013 - academic.oup.com
Reprogramming of somatic DNA by oocytes is inadequate and thus often causes an
abnormal epigenetic status in embryos derived from somatic cell nuclear transfer (SCNT) …