Obesity is typically associated with abnormal eating behaviors. Brain imaging studies in
humans implicate the involvement of dopamine (DA)-modulated circuits in pathologic eating …

Dopamine (DA) regulates emotional and motivational behavior through the mesolimbic
dopaminergic pathway. Changes in DA signaling in mesolimbic neurotransmission are …

Obesity is a major public health problem. The increasing number of obese individuals in the
US adds urgency to the efforts to understand the mechanisms underlying pathological …

Overeating in obese individuals shares similarities with the loss of control and compulsive
drug taking behavior observed in drug-addicted subjects. The mechanism of these …

Introduction: The neurotransmitter dopamine is important in the regulation of food intake. It is
hypothesised that obese people experience less reward from food due to lower striatal …

The obesity epidemic is believed to be driven by a food environment that promotes
consumption of inexpensive, convenient, high-calorie, palatable foods. Individual …

Neuroimaging techniques are starting to reveal significant overlap in the brain circuitry
underlying addiction and disorders of dyscontrol over rewarding behaviors (such as binge …

Dopamine is a neurotransmitter that plays a crucial role in adaptive behavior. A wealth of
studies suggests obesity-related alterations in the central dopamine system. The most direct …

Dopamine's role in inhibitory control is well recognized and its disruption may contribute to
behavioral disorders of discontrol such as obesity. However, the mechanism by which …

Both drug addiction and obesity can be defined as disorders in which the saliency value of
one type of reward (drugs and food, respectively) becomes abnormally enhanced relative to …