The Repressor Function of the Chlamydia Late Regulator EUO Is Enhanced by the Plasmid-Encoded Protein Pgp4

Q Zhang, CJ Rosario, LM Sheehan, SM Rizvi… - Journal of …, 2020 - Am Soc Microbiol
ABSTRACT A critical step in intracellular Chlamydia infection is the production of infectious
progeny through the expression of late genes. This differentiation step involves conversion …

The early gene product EUO is a transcriptional repressor that selectively regulates promoters of Chlamydia late genes

CJ Rosario, M Tan - Molecular microbiology, 2012 - Wiley Online Library
The obligate intracellular bacterium Chlamydia has an unusual developmental cycle in
which there is conversion between two forms that are specialized for either intracellular …

The transcriptional repressor EUO regulates both subsets of Chlamydia late genes

CJ Rosario, BR Hanson, M Tan - Molecular microbiology, 2014 - Wiley Online Library
The pathogenic bacterium C hlamydia replicates in a eukaryotic host cell via a
developmental cycle marked by temporal waves of gene expression. We have previously …

Euo is a developmental regulator that represses late genes and activates midcycle genes in Chlamydia trachomatis

OR Hakiem, SMA Rizvi, C Ramirez, M Tan - Mbio, 2023 - Am Soc Microbiol
The pathogenic bacterium Chlamydia reproduces via an unusual intracellular
developmental cycle in which it converts from a dividing form (reticulate body or RB) to an …

The chlamydial transcriptional regulator Euo is a key switch in cell form developmental progression but is not involved in the committed step to the formation of the …

CR Appa, NA Grieshaber, H Yang, A Omsland… - Msphere, 2024 - journals.asm.org
Bacteria in the genus Chlamydia are a significant health burden worldwide. They infect a
wide range of vertebrate animals, including humans and domesticated animals. In humans …

Regulation of Chlamydia gene expression by tandem promoters with different temporal patterns

CJ Rosario, M Tan - Journal of Bacteriology, 2016 - Am Soc Microbiol
Chlamydia is a genus of pathogenic bacteria with an unusual intracellular developmental
cycle marked by temporal waves of gene expression. The three main temporal groups of …

Temporal gene regulation during the chlamydial developmental cycle

M Tan - Intracellular Pathogens I: Chlamydiales, 2012 - Wiley Online Library
This chapter reviews the mechanisms of temporal gene regulation utilized during the three
main stages of the developmental cycle, as well as how transcription is silenced in …

Characterization of In Vitro DNA Binding Sites of the EUO Protein of Chlamydia psittaci

L Zhang, MM Howe, TP Hatch - Infection and immunity, 2000 - Am Soc Microbiol
The EUO gene of chlamydia is highly expressed early in the developmental cycle, relative to
other genes, but continues to be expressed throughout the active growth phases. The …

Transformation of Chlamydia muridarum reveals a role for Pgp5 in suppression of plasmid-dependent gene expression

Y Liu, C Chen, S Gong, S Hou, M Qi, Q Liu… - Journal of …, 2014 - Am Soc Microbiol
Transformation of Chlamydia trachomatis should greatly advance the chlamydial research.
However, significant progress has been hindered by the failure of C. trachomatis to induce …

Identification of a GrgA-Euo-HrcA transcriptional regulatory network in Chlamydia

W Wurihan, Y Zou, AM Weber, K Weldon, Y Huang… - Msystems, 2021 - Am Soc Microbiol
Chlamydia trachomatis is an obligate intracellular bacterium whose unique developmental
cycle consists of an infectious elementary body and a replicative reticulate body …