Inhibition of programmed death‐1 decreases neointimal hyperplasia after patch angioplasty

H Bai, Z Wang, M Li, P Sun, S Wei… - … Research Part B …, 2021 - Wiley Online Library
Neointimal hyperplasia remains an obstacle after vascular interventions. Programmed death‐
1 (PD‐1) antibody treatment decreases tumor cell proliferation and secretion of inflammatory …

[HTML][HTML] Programmed death-1 mediates venous neointimal hyperplasia in humans and rats

P Sun, Z Wang, W Liu, M Li, S Wei, Y Xu, Z Qiao… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Venous neointimal hyperplasia can be a problem after vein interventions. We hypothesized
that inhibiting programmed death-1 (PD-1) can decrease venous neointimal hyperplasia in a …

[HTML][HTML] Immune checkpoint programmed death-1 mediates abdominal aortic aneurysm and pseudoaneurysm progression

P Sun, L Zhang, Y Gu, S Wei, Z Wang, M Li… - Biomedicine & …, 2021 - Elsevier
Purpose The causes and pathogenetic mechanisms underlying abdominal aortic aneurysms
(AAAs) and pseudoaneurysms are not fully understood. We hypothesized that inhibiting …

Enhanced expression of programmed cell death 1 (PD-1) protein in benign vascular anomalies

CN Amaya, FH Wians Jr, BA Bryan, A Torabi - Pathology, 2017 - Elsevier
Summary Programmed cell death 1 (PD-1) and its ligands have been shown to play a
significant role in evasion of malignant tumour cells from the immune system. Last year, the …

Real-world treatment efficacy of anti-programmed death-1 combined with anti-angiogenesis therapy in non-small cell lung cancer patients

L Qiu, X Zhao, W Shi, S Sun, G Zhang, Q Sun, J Meng… - Medicine, 2020 - journals.lww.com
Abstract Anti-programmed death-1 (PD-1) therapy has been extensively used to treat
cancer. Recently, the combination of immunotherapy and anti-angiogenic therapy has …

Simultaneous blockade of programmed death 1 and vascular endothelial growth factor receptor 2 (VEGFR2) induces synergistic anti-tumour effect in vivo

S Yasuda, M Sho, I Yamato, H Yoshiji… - Clinical & …, 2013 - academic.oup.com
Recent basic and clinical studies have shown that the programmed death ligand (PD-L)/PD-
1 pathway has a significant role in tumour immunity, and its blockade has a therapeutic …

Impairment of the programmed cell death-1 pathway increases atherosclerotic lesion development and inflammation

D Bu, M Tarrio, E Maganto-Garcia… - … , and vascular biology, 2011 - Am Heart Assoc
Objective—Programmed cell death-1 (PD-1) is a member of the CD28 superfamily that
delivers negative signals on interaction with its 2 ligands, PD-L1 and PD-L2. We studied the …

PD-L1 (Programmed Death Ligand 1) regulates T-cell differentiation to control adaptive venous remodeling

Y Matsubara, L Gonzalez, G Kiwan, J Liu… - … , and vascular biology, 2021 - Am Heart Assoc
Objective: Patients with end-stage renal disease depend on hemodialysis for survival.
Although arteriovenous fistulae (AVF) are the preferred vascular access for hemodialysis …

PD-1/PD-L1 blockade accelerates the progression of atherosclerosis in cancer patients

M Dong, T Yu, G Tse, Z Lin, C Lin, N Zhang… - Current problems in …, 2023 - Elsevier
Abstract PD-1 (programed death-1)/PD-L1 (programed death-1 ligand) blockade represents
a major breakthrough of anti-cancer therapies, however, it may come with increased risk of …

[HTML][HTML] A review of the current state in neointimal hyperplasia development following endovascular intervention and minor emphasis on new horizons in …

R Dinc - Translational and Clinical Pharmacology, 2023 - ncbi.nlm.nih.gov
Endovascular strategies play a vital role in the treatment of peripheral arterial disease
(PAD). However, luminal loss or restenosis after endovascular intervention remains a …