Aortic aneurysms: current pathogenesis and therapeutic targets
MJ Cho, MR Lee, JG Park - Experimental & Molecular Medicine, 2023 - nature.com
Aortic aneurysm is a chronic disease characterized by localized expansion of the aorta,
including the ascending aorta, arch, descending aorta, and abdominal aorta. Although aortic …
including the ascending aorta, arch, descending aorta, and abdominal aorta. Although aortic …
The mechanism and therapy of aortic aneurysms
Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …
Cellular mechanisms of aortic aneurysm formation
RA Quintana, WR Taylor - Circulation Research, 2019 - Am Heart Assoc
Aortic aneurysms are a common vascular disease in Western populations that can involve
virtually any portion of the aorta. Abdominal aortic aneurysms are much more common than …
virtually any portion of the aorta. Abdominal aortic aneurysms are much more common than …
Mechanisms of aortic aneurysm formation: translating preclinical studies into clinical therapies
FM Davis, DL Rateri, A Daugherty - Heart, 2014 - heart.bmj.com
Aneurysms are common in the abdominal and thoracic regions of the aorta. While generally
asymptomatic, progression of aneurysms is associated with the devastating consequences …
asymptomatic, progression of aneurysms is associated with the devastating consequences …
Cellular signaling in abdominal aortic aneurysm
Z Li, W Kong - Cellular signalling, 2020 - Elsevier
Abdominal aortic aneurysms (AAAs) are highly lethal cardiovascular diseases without
effective medications. However, the molecular and signaling mechanisms remain unclear. A …
effective medications. However, the molecular and signaling mechanisms remain unclear. A …
Reflections on the pathogenesis of abdominal aortic aneurysms
RW Thompson - Cardiovascular Surgery, 2002 - Elsevier
The care of patients with abdominal aortic aneurysms (AAAs) has served as a benchmark of
progress in vascular surgery for more than 50 years. Beginning with the introduction of …
progress in vascular surgery for more than 50 years. Beginning with the introduction of …
Pathogenic mechanisms and the potential of drug therapies for aortic aneurysm
B Liu, DJ Granville, J Golledge… - American Journal of …, 2020 - journals.physiology.org
Aortic aneurysm is a permanent focal dilation of the aorta. It is usually an asymptomatic
disease but can lead to sudden death due to aortic rupture. Aortic aneurysm-related …
disease but can lead to sudden death due to aortic rupture. Aortic aneurysm-related …
[HTML][HTML] Challenges and opportunities in abdominal aortic aneurysm research
M Wassef, GR Upchurch Jr, H Kuivaniemi… - Journal of vascular …, 2007 - Elsevier
Abdominal Aortic Aneurysms (AAAs) are associated with advanced age, male gender,
cigarette smoking, atherosclerosis, hypertension, and genetic predisposition. Basic research …
cigarette smoking, atherosclerosis, hypertension, and genetic predisposition. Basic research …
Vascular smooth muscle cells in aortic aneurysm: from genetics to mechanisms
Aortic aneurysm, including thoracic aortic aneurysm and abdominal aortic aneurysm, is the
second most prevalent aortic disease following atherosclerosis, representing the ninth …
second most prevalent aortic disease following atherosclerosis, representing the ninth …
Hereditary influence in thoracic aortic aneurysm and dissection
Thoracic aortic aneurysm is a potentially life-threatening condition in that it places patients at
risk for aortic dissection or rupture. However, our modern understanding of the pathogenesis …
risk for aortic dissection or rupture. However, our modern understanding of the pathogenesis …