Retinoblastoma-binding protein-6 (RBBP6) plays a facilitating role, through its RING finger-
like domain, in the ubiquitination of p53 by Hdm2 that is suggestive of E4-like activity …

The retinoblastoma binding protein 6 (RBBP6), a p53 negative regulator, is essential for
embryonic development. Its loss-of-function phenotype is similar to mouse double minute …

As a step towards better integrating protein three-dimensional (3D) structural information in
cancer systems biology, the Northeast Structural Genomics Consortium (NESG)(www. nesg …

RBBP6 (retinoblastoma binding protein 6) is a 250-kDa multifunctional protein that interacts
with both p53 and pRb and has been implicated in mRNA processing. It has also been …

Retinoblastoma binding protein 6 (RBBP6) interacts with both p53 and pRb, and has been
identified as an E3 ubiquitin ligase due to the presence of a RING finger domain. RBBP6 …

The human retinoblastoma binding protein 6 (RBBP6) is implicated in esophageal, lung,
hepatocellular and colon cancers. Furthermore, RBBP6 was identified as a strong marker for …

Abstract The ErbB3 binding protein Ebp1 has been implicated in a number of human
cancers. Ebp1 includes 2 isoforms, p48 and p42, that exhibit different cellular activities. Here …

Regulation of the transcriptional response to the tumor suppressor p53 occurs at many
levels, including control of its transcriptional activity, and of its stability and concentration …

Abstract Retinoblastoma binding protein 6 (RBBP6) is a nuclear protein, previously
implicated in the regulation of cell cycle and apoptosis. The human RBBP6 gene codes for …

Inactivation of retinoblastoma protein (Rb) plays a critical role in the development of human
malignancies. It has been shown that Rb is degraded through a proteasome-dependent …