Generation and comprehensive characterization of induced pluripotent stem cells for translational research

CC MacArthur, S Pradhan, N Wetton… - Regenerative …, 2019 - Taylor & Francis
Induced pluripotent stem cells (iPSCs) hold immense potential in disease modeling, drug
discovery and regenerative medicine. Despite advances in reprogramming methods …

Establishing iPSC cell banks derived using reagents and workflows optimized for cell therapy manufacturing

CC MacArthur, S Pradhan, S Switalski, M Landon… - Cytotherapy, 2019 - Elsevier
Background & Aim Induced pluripotent stem cell (iPSC) research is rapidly moving towards
translational and clinical applications. These applications require robust and consistent …

Ten years of progress and promise of induced pluripotent stem cells: historical origins, characteristics, mechanisms, limitations, and potential applications

AE Omole, AOJ Fakoya - PeerJ, 2018 - peerj.com
The discovery of induced pluripotent stem cells (iPSCs) by Shinya Yamanaka in 2006 was
heralded as a major breakthrough of the decade in stem cell research. The ability to …

Current reprogramming systems in regenerative medicine: from somatic cells to induced pluripotent stem cells

C Hu, L Li - Regenerative medicine, 2016 - Taylor & Francis
Induced pluripotent stem cells (iPSCs) paved the way for research fields including cell
therapy, drug screening, disease modeling and the mechanism of embryonic development …

Induced pluripotent stem cells in regenerative medicine

LS Pane, I My, A Moretti - Regenerative Medicine-from Protocol to Patient …, 2016 - Springer
The conversion of somatic cells into pluripotent cells is transforming the way diseases are
studied and treated. Owing to their ability to differentiate into any cell type in the body and …

Induced pluripotent stem cells and personalized medicine: current progress and future perspectives

YS Chun, K Byun, B Lee - Anatomy & cell biology, 2011 - synapse.koreamed.org
Generation of induced pluripotent stem cells (iPSCs) has revolutionized the field of
regenerative medicine by providing researchers with a unique tool to derive disease-specific …

Overcoming barriers to the clinical utilization of iPSCs: reprogramming efficiency, safety and quality

S Cao, K Loh, Y Pei, W Zhang, J Han - Protein & cell, 2012 - Springer
Differentiated cells can be reprogrammed into pluripotent stem cells, known as “induced
pluripotent stem cells”(iPSCs), through the overexpression of defined transcription factors …

[HTML][HTML] Induced Pluripotent Stem Cells: Advances and Applications in Regenerative Medicine

I Kizub, A Rozhok, G Bilousova - Possibilities and Limitations in …, 2022 - intechopen.com
Reprogramming adult somatic cells into induced pluripotent stem cells (iPSCs) through the
ectopic expression of reprogramming factors offers truly personalized cell-based therapy …

An overview of direct somatic reprogramming: the ins and outs of iPSCs

S Menon, S Shailendra, A Renda, M Longaker… - International journal of …, 2016 - mdpi.com
Stem cells are classified into embryonic stem cells and adult stem cells. An evolving
alternative to conventional stem cell therapies is induced pluripotent stem cells (iPSCs) …

Progress and promise towards safe induced pluripotent stem cells for therapy

A Seifinejad, M Tabebordbar, H Baharvand… - Stem Cell Reviews and …, 2010 - Springer
The recent generation of induced pluripotent stem cells (iPSCs) from somatic cells provides
an invaluable resource for drug or toxicology screening, medical research, and patient …