Frontotemporal dementia: clinicopathological correlations

MS Forman, J Farmer, JK Johnson… - Annals of Neurology …, 2006 - Wiley Online Library
Objective Frontotemporal lobar degeneration (FTLD) is characterized by impairments in
social, behavioral, and/or language function, but postmortem studies indicate that multiple …

Advances in neuroimaging in frontotemporal dementia

E Gordon, JD Rohrer, NC Fox - Journal of Neurochemistry, 2016 - Wiley Online Library
Frontotemporal dementia (FTD) is a clinically and neuroanatomically heterogeneous
neurodegenerative disorder with multiple underlying genetic and pathological causes …

Therapy and clinical trials in frontotemporal dementia: past, present, and future

RM Tsai, AL Boxer - Journal of neurochemistry, 2016 - Wiley Online Library
Frontotemporal dementia (FTD) is a common form of dementia with heterogeneous clinical
presentations and distinct clinical syndromes. This article will review currently available …

The genetics and neuropathology of frontotemporal lobar degeneration

A Sieben, T Van Langenhove, S Engelborghs… - Acta …, 2012 - Springer
Frontotemporal lobar degeneration (FTLD) is a heterogeneous group of disorders
characterized by disturbances of behavior and personality and different types of language …

Magnetic resonance imaging signatures of tissue pathology in frontotemporal dementia

JL Whitwell, KA Josephs, MN Rossor… - Archives of …, 2005 - jamanetwork.com
Background The pathologic substrates of frontotemporal dementia (FTD) are difficult to
predict in vivo. Objective To determine whether different pathologic substrates of FTD have …

The genetic and pathological classification of familial frontotemporal dementia

HR Morris, MN Khan, JC Janssen, JM Brown… - Archives of …, 2001 - jamanetwork.com
Background Frontotemporal dementia (FTD) is an important cause of neurodegenerative
dementia, particularly in younger patients. TAUhas been identified as the gene responsible …

Frontotemporal dementia: therapeutic interventions

MF Mendez - Dementia in Clinical Practice, 2009 - karger.com
The management of frontotemporal dementia (FTD), a disorder characterized by varied
behavioralsymptoms, primarily involves the use of psychoactive medications. Although there …

Imaging and fluid biomarkers in frontotemporal dementia

LH Meeter, LD Kaat, JD Rohrer… - Nature Reviews …, 2017 - nature.com
Frontotemporal dementia (FTD), the second most common type of presenile dementia, is a
heterogeneous neurodegenerative disease characterized by progressive behavioural …

Mouse models of frontotemporal dementia

ED Roberson - Annals of neurology, 2012 - Wiley Online Library
The pace of discovery in frontotemporal dementia (FTD) has accelerated dramatically with
the discovery of new genetic causes and pathological substrates of the disease. MAPT/tau …

Update on the neuropathological diagnosis of frontotemporal dementias

JQ Trojanowski, D Dickson - Journal of Neuropathology & …, 2001 - academic.oup.com
Previous criteria for Frontotemporal Dementia have primarily been designed for research
purposes (1–5). An international group of experts on clinical and neuropathological aspects …