The International Metastatic Renal Cell Carcinoma Database Consortium model as a prognostic tool in patients with metastatic renal cell carcinoma previously treated …

JJ Ko, W Xie, N Kroeger, J Lee, BI Rini, JJ Knox… - The lancet …, 2015 - thelancet.com
Background Previous prognostic models for second-line systemic therapy in patients with
metastatic renal cell carcinoma have not been studied in the setting of targeted therapy. We …

Predictors, utilization patterns, and overall survival of patients undergoing metastasectomy for metastatic renal cell carcinoma in the era of targeted therapy

M Sun, CP Meyer, JA Karam, G de Velasco… - European Journal of …, 2018 - Elsevier
Introduction Metastasectomy (MSX) is considered a treatment option in patients with
metastatic renal cell carcinoma (mRCC) at diagnosis, but its role in the targeted therapy era …

Survival outcome and treatment response of patients with late relapse from renal cell carcinoma in the era of targeted therapy

N Kroeger, TK Choueiri, JL Lee, GA Bjarnason… - European urology, 2014 - Elsevier
Background A subset of primarily localized renal cell carcinoma (RCC) patients will
experience disease recurrence≥ 5 yr after initial nephrectomy. Objective To characterize …

[HTML][HTML] Utilization and efficacy of second-line targeted therapy in metastatic renal cell carcinoma: data from a national registry

R Lakomy, A Poprach, Z Bortlicek, B Melichar… - BMC cancer, 2017 - Springer
Background It is well known that patient characteristics and survival outcomes in
randomized trials may not necessarily be similar to those in real-life clinical practice. The …

[HTML][HTML] Second line treatment of metastatic renal cell carcinoma: The Institut Gustave Roussy experience with targeted therapies in 251 consecutive patients

A Levy, J Menard, L Albiges, Y Loriot… - European Journal of …, 2013 - Elsevier
BACKGROUND: Sequential treatment is currently the standard of care in metastatic renal
cell carcinoma (mRCC). However, very little is known on how many patients (pts) can …

The distribution of metastatic renal cell carcinoma by presenting tumor stage in the modern era

E Sharp, A Guduru, AM May, L Lombardo… - Clinical Genitourinary …, 2022 - Elsevier
Introduction There is a stage migration for detection of kidney cancer, thus we aim to
evaluate the distribution of metastatic renal cell carcinoma by presenting clinical T stage …

[HTML][HTML] Synchronous versus metachronous metastatic disease: impact of time to metastasis on patient outcome—results from the International Metastatic Renal Cell …

F Donskov, W Xie, A Overby, JC Wells… - European urology …, 2020 - Elsevier
Background Patients with metastatic renal cell carcinoma (mRCC) may present with primary
metastases (synchronous disease) or develop metastases during follow-up (metachronous …

[HTML][HTML] Outcome of treatment discontinuation in patients with metastatic renal cell carcinoma and no evidence of disease following targeted therapy with or without …

M Johannsen, M Staehler, CH Ohlmann, A Flörcken… - Annals of oncology, 2011 - Elsevier
Background It is unknown if discontinuation of targeted therapy (TT) and readministration in
case of recurrence is feasible in patients with metastatic renal cell carcinoma (mRCC) in …

Prognostic factors for survival in metastatic renal cell carcinoma: retrospective analysis from 109 consecutive patients

G Citterio, A Bertuzzi, M Tresoldi, L Galli, G Di Lucca… - European …, 1997 - karger.com
Objective: Metastatic renal cell cancer (RCC) portends a bad prognosis, but survival is quite
different among different patients. The objective of this study was to determine prognostic …

[HTML][HTML] Nephrectomy improves the survival of metastatic renal cell cancer patients with moderate to good performance status—results from a Finnish nation-wide …

L Laru, H Ronkainen, P Ohtonen… - World Journal of Surgical …, 2021 - Springer
Background The purpose of this study was to evaluate the effects of cytoreductive
nephrectomy (CN) and metastasectomies on the survival of patients with synchronous …