Over the past several decades capsaicin, a natural product of certain species of red pepper,
has been found to have a broad range of physiological effects in adult animals. Recent …

Capsaicin is a principle constituent in a large variety of red peppers (eg, Capsicum annuum,
Capsicum frutescens), and it is to this and closely related substances that the pungency of …

Capsaicin is the pungent ingredient in a wide variety of red peppers of the genus Capsicum.
Chemically it is a derivative of vanillyl amide, 8-methyl-N-vanillyl-6-nonenamide (Fig. 1) with …

Capsaicin is now widely used to explore and/or prove the role of peptide-containing primary
afferent neurones in different somato-and viscerosensory functions. The present paper deals …

In the late fifties and sixties Jancso published a series of papers on 'the peculiar
pharmacological effect of capsaicin Capsaicin or 8-methyl-N-vanillyi-6-nonenamide is the …

Systemic capsaicin treatment of neonatal and adult rats is known to affect unmyelinated
afferents. However, the systemic route of administration presents several disadvantages and …

The morphological effects of systemic capsaicin treatment have been studied in adult rats.
Light and electron microscopy revealed that a subpopulation of small-to-medium sized B …

The responsiveness to noxious thermal, mechanical, and chemical stimuli was examined in
adult rats that had been treated neonatally with capsaicin. A range of capsaicin doses was …

The present study shows that systemic capsaicin in adult rats results in a significant loss of
axons in the subepidermal nerve plexus of the posterior leg but no loss of axons in the sural …

Capsaicin applied to the soma of fast and slow conducting primary afferent fibers had a
depolarizing action associated with an increase in membrane conductance. The …