Molecular and epigenetic modes of Fumonisin B1 mediated toxicity and carcinogenesis and detoxification strategies

T Arumugam, T Ghazi… - Critical Reviews in …, 2021 - Taylor & Francis
Abstract Fumonisin B1 (FB1) is a natural contaminant of agricultural commodities that has
displayed a myriad of toxicities in animals. Moreover, it is known to be a hepatorenal …

Molecular mechanisms of fumonisin B1-induced toxicities and its applications in the mechanism-based interventions

X Liu, L Fan, S Yin, H Chen, H Hu - Toxicon, 2019 - Elsevier
Abstract Fumonisin B1 (FB1), the most toxic member of fumonisins, is one of the most
common mycotoxins contaminating feed and food. It has been shown to produce pleiotropic …

Fumonisin B1 and the kidney: Modes of action for renal tumor formation by fumonisin B1 in rodents

S Müller, W Dekant, A Mally - Food and chemical toxicology, 2012 - Elsevier
The mycotoxin fumonisin B1 (FB1) is an important contaminant of maize and maize-based
products. In rodent toxicity studies, FB1 was shown to be hepato-and nephrotoxic, and to …

Fumonisin B1: Mechanisms of toxicity and biological detoxification progress in animals

J Chen, Z Wei, Y Wang, M Long, W Wu… - Food and chemical …, 2021 - Elsevier
Abstract Fumonisin B1 (FB 1) is a toxic secondary metabolite produced by the Fusarium
molds that can contaminate food and feed. It has been found that FB 1 can cause systemic …

The natural occurrence, toxicity mechanisms and management strategies of Fumonisin B1: A review

Z Gao, K Luo, Q Zhu, J Peng, C Liu, X Wang, S Li… - Environmental …, 2023 - Elsevier
Abstract Fumonisin B1 (FB1) contaminates various crops, causing huge losses to agriculture
and livestock worldwide. This review summarizes the occurrence regularity, toxicity, toxic …

Modulation of selected cell signaling genes in mouse liver by fumonisin B1

N Bhandari, P Raghubir - Chemico-biological interactions, 2002 - Elsevier
Fumonisin B1 (FB1) is a naturally occurring mycotoxin produced primarily by Fusarium
verticillioides and related fungi, common contaminants of corn throughout the world. FB1 is a …

Deletion of IFN-γ Reduces Fumonisin-Induced Hepatotoxicity in Mice via Alterations in Inflammatory Cytokines and Apoptotic Factors

RP Sharma, Q He, VJ Johnson - Journal of interferon & cytokine …, 2003 - liebertpub.com
Fumonisin B1 (FB1) produces species-specific and organ-specific toxicity, including equine
leukoencephalomalacia, porcine pulmonary edema, and hepatic or renal damage in other …

[HTML][HTML] Obesity promotes fumonisin B1 hepatotoxicity

L Dopavogui, M Régnier, A Polizzi, Q Ponchon… - Science of the Total …, 2023 - Elsevier
Obesity, which is a worldwide public health issue, is associated with chronic inflammation
that contribute to long-term complications, including insulin resistance, type 2 diabetes and …

Fumonisin toxicity and mechanism of action: overview and current perspectives

KA Voss, RT Riley - Food Safety, 2013 - jstage.jst.go.jp
Fumonisins are mycotoxins produced predominantly by Fusarium verticillioides and F.
proliferatum. They contaminate maize and maize-based foods throughout the world …

Endoplasmic reticulum stress-mediated autophagy activation attenuates fumonisin B1 induced hepatotoxicity in vitro and in vivo

MP Singh, SC Kang - Food and chemical toxicology, 2017 - Elsevier
Although pathological characteristics of fumonisin B1 are known to induce hepatic injury
over prolonged periods, the cellular defense mechanisms against the detrimental effects of …