Background There is a clinical need for treatments that can slow or prevent the growth of an
abdominal aortic aneurysm, not only to reduce the need for surgery, but to provide a means …

Background It has been suggested that diabetes medications, such as metformin, may have
effects that inhibit abdominal aortic aneurysm (AAA) growth. The aim of this study was to …

Objective A meta-analysis of the association between metformin prescription and abdominal
aortic aneurysm (AAA) growth and events (rupture or surgical repair) was performed …

Worldwide about 20 million people have an abdominal aortic aneurysm (AAA) and rupture
leads to approximately 200 000 deaths annually. To prevent rupture, early detection and …

Epidemiological and experimental studies have pointed to a protective effect of metformin in
abdominal aortic aneurysm (AAA), but its efficacy in preventing AAA expansion remains to …

Conclusions Metformin seems to be associated with a decrease in AAA risk and
enlargement rate. Evidence for the other classes is lacking. Studies evaluating the …

Background Abdominal aortic aneurysm (AAA) is a cardiovascular disease characterized by
a high mortality rate when ruptured. Some studies suggest a potential inverse correlation …

Abdominal aortic aneurysm (AAA) may lead to rupture and death if left untreated. While
endovascular or surgical repair is generally recommended for AAA greater than 5–5.5 cm …

Objectives Currently there is no drug therapy for abdominal aortic aneurysm (AAA) and most
previous investigations have focused on imaging rather than clinical outcomes. The aim of …

Background Multiple observational studies have associated metformin prescription with
reduced progression of abdominal aortic aneurysm (AAA). The Metformin Aneurysm Trial …