Biological and Clinical Relevance of Anti‐Prothrombin Antibodies

A Ghirardello, N Bizzaro, S Zampieri… - Annals of the New …, 2007 - Wiley Online Library
Anti‐prothrombin (anti‐PT) antibodies are recently identified antibodies directed toward a
phospholipid‐binding protein (prothrombin), which deserve attention for the reported clinical …

Significance of antiprothrombin antibodies in patients with systemic lupus erythematosus: clinical evaluation of the antiprothrombin assay and the …

A Tsutsumi, T Hayashi, Y Chino, M Mamura… - Modern …, 2006 - Taylor & Francis
Antibodies against prothrombin are detected by enzyme immunoassays (EIA) in sera of
patients with antiphospholipid syndrome (APS). However, there are two methods for …

[引用][C] Specificities, properties, and clinical significance of antiprothrombin antibodies

O Amengual, T Atsumi, T Koike - Arthritis & Rheumatism …, 2003 - Wiley Online Library
Antibodies against phospholipid-binding proteins, such as 2-glycoprotein I (2GPI) and
prothrombin, are associated with the clinical manifestations of the antiphospholipid …

Phospholipid autoantibodies (nonanticardiolipin)-antiprothrombin antibodies

F Pregnolato, CB Chighizola - Autoantibodies, 2014 - Elsevier
Prothrombin (PT) provides one of the main antigenic targets of antiphospholipid antibodies
(aPL), the serologic markers of antiphospholipid syndrome (APS). First described in 1983 …

Antibodies to prothrombin

ML Bertolaccini - Lupus, 2012 - journals.sagepub.com
Research on antiphospholipid antibodies (aPL) and the thrombotic manifestations
associated with these antibodies has grown since the description of anticardiolipin …

Antiprothrombin antibodies—are they worth assaying?

T Atsumi, O Amengual, S Yasuda, T Koike - Thrombosis Research, 2004 - Elsevier
According to the preliminary classification criteria of the antiphospholipid syndrome
(APS)(Sapporo Criteria), β2-glycoprotein I (β2GPI)-dependent anticardiolipin antibodies …

Clinical relevance of antiprothrombin antibodies

T Atsumi, T Koike - Autoimmunity Reviews, 2002 - Elsevier
Antiprotrombin antibodies belong to the family of antiphospholipid antibodies (aPLs). The
clinical relevance of antiprothrombin antibodies has not been established and it depends on …

[HTML][HTML] Anti‐prothrombin antibodies predict thrombosis in patients with systemic lupus erythematosus: a 15‐year longitudinal study

N Bizzaro, A Ghirardello, S Zampieri, L Iaccarino… - Journal of Thrombosis …, 2007 - Elsevier
Objective: To evaluate the role of anti‐prothrombin (anti‐PT) antibodies in predicting
thrombosis in patients with systemic lupus erythematosus (SLE). Methods: An inception …

Anti-β2-glycoprotein I and anti-prothrombin antibodies in patients with the 'antiphospholipid'syndrome: Immunological specificity and clotting profiles

DA Kandiah, SA Krilis - Lupus, 1998 - journals.sagepub.com
Lupus anticoagulant (LA) antibodies have been shown to be directed to protein-
phospholipid complexes. In this study, we report on LA antibodies from patients with the …

Laboratory testing for non-criteria antiphospholipid antibodies: anti-phosphatidylserine/prothrombin antibodies (aPS/PT)

KMJ Devreese - Hemostasis and Thrombosis: Methods and Protocols, 2023 - Springer
Since the discovery that antiphospholipid antibodies (aPL) bind to a cofactor at the
phospholipid membrane, the proteins beta-2-glycoprotein I (β2GPI) and prothrombin …