Atherogenesis has been traditionally viewed as a metabolic disease representing arterial
obstruction by fatty deposits in its wall. Today, it is believed that atherogenesis involves …

Inflammation is now recognized as being pivotal in the pathogenesis of atherosclerosis. This
review highlights key concepts in our current understanding of the role of inflammation in the …

Modern-day treatment of atherosclerosis has arisen primarily from an understanding of the
epidemiology of the disease rather than its pathophysiology, in that risk factors have …

Atherosclerosis is a high-cost disease and its complications still represent the first cause of
death in most industrialized countries. Efficacious prevention includes treatment of the most …

Inflammation is a critical component in the development of coronary heart disease (CHD),
specifically in the process of atherogenesis. Human translational and preclinical studies …

Cardiovascular diseases cause considerable health and economic burden, as they are the
leading cause of disability and death in the western world. Inactivity, hypertension, obesity …

Recent evidence suggests that vascular inflammation plays important role in the
pathogenesis and the clinical evolution of atherosclerosis. Several circulating inflammatory …

Cardiovascular disease (CVD) has been associated with the so-called traditional risk
factors, such as hypertension, hypercholesterolemia and cigarette smoking. Chronic …

Inflammatory biomarkers play a pivotal role in atherosclerotic lesions. The plasma levels of
these markers are predictive of adverse outcomes such as myocardial infarction and …

Recent advances in basic science have shown that atherosclerosis should be considered as
a chronic inflammatory process, and that a pivotal role of inflammation is evident from …