Inflammatory therapeutic targets in coronary atherosclerosis—from molecular biology to clinical application

F Linden, G Domschke, C Erbel… - Frontiers in …, 2014 - frontiersin.org
Atherosclerosis is the leading cause of death worldwide. Over the past two decades, it has
been clearly recognized that atherosclerosis is an inflammatory disease of the arterial wall …

Inflammatory and non-invasive vascular markers: the multimarker approach for risk stratification in coronary artery disease

I Ikonomidis, K Stamatelopoulos, J Lekakis… - Atherosclerosis, 2008 - Elsevier
Current thinking supports the notion that several inflammatory proteins intervene with
endothelium and haemostatic factors leading to plaque formation and rupture. Of these, C …

Integrating diet and inflammation to calculate cardiovascular risk

J Gambardella, G Santulli - Atherosclerosis, 2016 - atherosclerosis-journal.com
In the last decade, several studies strengthened the idea that a diffuse and systemic
inflammation is functionally associated with cardiovascular disease (CVD). The mechanism …

Inflammation in atherosclerosis: a cause or a result of vascular disorders?

I Manduteanu, M Simionescu - Journal of cellular and …, 2012 - Wiley Online Library
Sound data support the concept that in atherosclerosis, inflammation and dyslipidemia
intersect each other and that irrespective of the initiator, both participate from the early …

Inflammation and coronary artery disease

U Ikeda - Current Vascular Pharmacology, 2003 - ingentaconnect.com
Several evidences, ranging from in vitro experiments, pathologic analysis and epidemiologic
studies, show that atherosclerosis is intrinsically an inflammatory disease. The plasma …

Inflammation in coronary atherosclerosis and its therapeutic implications

NJ Montarello, MT Nguyen, DTL Wong… - … drugs and therapy, 2022 - Springer
Atherosclerotic coronary artery disease has a complex pathogenesis which extends beyond
cholesterol intimal infiltration. It involves chronic inflammation of the coronary artery wall …

Inflammation and metabolic dysfunction: links to cardiovascular diseases

A Taube, R Schlich, H Sell… - American journal of …, 2012 - journals.physiology.org
Abdominal obesity is a major risk factor for cardiovascular disease, and recent studies
highlight a key role of adipose tissue dysfunction, inflammation, and aberrant adipokine …

Inflammatory related cardiovascular diseases: from molecular mechanisms to therapeutic targets

C Sardu, G Paolisso, R Marfella - Current pharmaceutical …, 2020 - ingentaconnect.com
Inflammation is a pathogenic response to multiple factors, that causes over-activation of
different molecules and pro-inflammatory cellular lines. Different behavioral factors and risk …

[HTML][HTML] C-reactive protein, inflammation and coronary heart disease

AK Shrivastava, HV Singh, A Raizada… - The Egyptian Heart …, 2015 - Elsevier
Inflammation is widely considered to be an important contributing factor of the
pathophysiology of coronary heart disease (CHD), and the inflammatory cascade is …

Treating inflammation in atherosclerotic cardiovascular disease: emerging therapies

R Klingenberg, GK Hansson - European heart journal, 2009 - academic.oup.com
Atherosclerosis constitutes the underlying disease to the clinical manifestations of
myocardial infarction, stroke, and gangrene. Despite the success of statins, prevention of …