Hyperactivation of the amygdala correlates with impaired social play behavior of prepubertal male rats in a maternal immune activation model

F Vitor-Vieira, FC Vilela, A Giusti-Paiva - Behavioural Brain Research, 2021 - Elsevier
Maternal infection during pregnancy is an environmental risk factor for neurodevelopmental
dysfunction, such as autism spectrum disorder (ASD). This study investigated the effect of …

Influence of maternal immune activation on autism-like symptoms and coping strategies in male offspring

F Vitor-Vieira, PP Patriarcha, VCT Rojas… - Physiology & …, 2024 - Elsevier
Maternal immune activation (MIA) caused by exposure to pathogens or inflammation during
critical periods of gestation increased susceptibility to neurodevelopmental disorders …

Maternal immune activation induces autism-like behavior and reduces brain-derived neurotrophic factor levels in the hippocampus and offspring cortex of C57BL/6 …

ML Dutra, P Dias, V Freiberger, L Ventura… - Neuroscience …, 2023 - Elsevier
Prenatal factors such as viral or bacterial infections occurring mainly during the first
trimesters of pregnancy can increase the incidence of autism spectrum disorder (ASD) in …

Gender-dependent effects of maternal immune activation on the behavior of mouse offspring

ICY Xuan, DR Hampson - PloS one, 2014 - journals.plos.org
Autism spectrum disorders are neurodevelopmental disorders characterized by two core
symptoms; impaired social interactions and communication, and ritualistic or repetitive …

Behavioral alterations and decreased number of parvalbumin-positive interneurons in Wistar rats after maternal immune activation by lipopolysaccharide: sex matters

I Vojtechova, K Maleninska, V Kutna, O Klovrza… - International journal of …, 2021 - mdpi.com
Maternal immune activation (MIA) during pregnancy represents an important environmental
factor in the etiology of schizophrenia and autism spectrum disorders (ASD). Our goal was to …

Sexually dimorphic effects of a prenatal immune challenge on social play and vasopressin expression in juvenile rats

PV Taylor, AH Veenema, MJ Paul, R Bredewold… - Biology of sex …, 2012 - Springer
Background Infectious diseases and inflammation during pregnancy increase the offspring's
risk for behavioral disorders. However, how immune stress affects neural circuitry during …

Maternal immune activation impairs cognitive flexibility and alters transcription in frontal cortex

DA Amodeo, CY Lai, O Hassan, EA Mukamel… - Neurobiology of …, 2019 - Elsevier
Background Epidemiological studies suggest that the risk of neurodevelopmental disorders
such as autism spectrum disorder (ASD) and schizophrenia is increased by prenatal …

Maternal immune activation induces autism-like changes in behavior, neuroinflammatory profile and gut microbiota in mouse offspring of both sexes

AM Tartaglione, A Villani, MA Ajmone-Cat… - Translational …, 2022 - nature.com
Abstract Autism Spectrum Disorder (ASD) is a sex-biased neurodevelopmental disorder with
a male to female prevalence of 4: 1, characterized by persistent deficits in social …

Maternal immune activation in mice only partially recapitulates the autism spectrum disorders symptomatology

D Vigli, G Palombelli, S Fanelli, G Calamandrei… - Neuroscience, 2020 - Elsevier
Prenatal viral/bacterial infections are considered risk factors for autism spectrum disorders
(ASD) and rodent models of maternal immune activation (MIA) have been developed and …

[HTML][HTML] Maternal infection during pregnancy aggravates the behavioral response to an immune challenge during adolescence in female rats

CGJ Guerrin, EFJ de Vries, K Prasad… - Behavioural Brain …, 2023 - Elsevier
Prenatal and early postnatal infection have been associated with changes in microglial
activity and the development of psychiatric disorders. Here, we investigated the effect of …