[HTML][HTML] DNA methylation pattern in human zygotes and developing embryos
H Fulka, M Mrazek, O Tepla, J Fulka - Reproduction, 2004 - rep.bioscientifica.com
We report on observations of the global methylation/demethylation pattern of both pronuclei
in human zygotes and in early embryos up to the blastocyst stage. Our results demonstrate …
in human zygotes and in early embryos up to the blastocyst stage. Our results demonstrate …
Aberrant methylation patterns at the two‐cell stage as an indicator of early developmental failure
W Shi, T Haaf - Molecular Reproduction and Development …, 2002 - Wiley Online Library
The fertilized mouse egg actively demethylates the paternal genome within a few hours after
fertilization, whereas the maternal genome is only passively demethylated by a replication …
fertilization, whereas the maternal genome is only passively demethylated by a replication …
Genome-wide methylation patterns in normal and uniparental early mouse embryos
SC Barton, KL Arney, W Shi, A Niveleau… - Human Molecular …, 2001 - academic.oup.com
In the normal diploid mouse embryo, active demethylation of the paternal genome but not of
the maternal genome occurs within only a few hours and in a highly coordinated fashion as …
the maternal genome occurs within only a few hours and in a highly coordinated fashion as …
Dynamics of DNA‐demethylation in early mouse and rat embryos developed in vivo and in vitro
I Zaitseva, S Zaitsev, N Alenina, M Bader… - Molecular …, 2007 - Wiley Online Library
Virtually all mammalian species including mouse, rat, pig, cow, and human, but not sheep
and rabbit, undergo genome‐wide epigenetic reprogramming by demethylation of the male …
and rabbit, undergo genome‐wide epigenetic reprogramming by demethylation of the male …
Alterations of DNA methylation patterns in germ cells and Sertoli cells from developing mouse testis
H Coffigny, C Bourgeois, M Ricoul… - Cytogenetics and cell …, 1999 - karger.com
In situ alterations of DNA methylation were studied between 14 d postcoitum and 4 d
postpartum in Sertoli cells and germ cells from mouse testis, using anti-5-methylcytosine …
postpartum in Sertoli cells and germ cells from mouse testis, using anti-5-methylcytosine …
Methylation levels of maternal and paternal genomes during preimplantation development
SK HOWLETT, W REIK - Development, 1991 - journals.biologists.com
The methylation status of three highly repeated sequences was studied in sperm, eggs and
preimplantation embryos with different combinations of parental chromosomes. High levels …
preimplantation embryos with different combinations of parental chromosomes. High levels …
Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development
M Monk, M Boubelik, S Lehnert - Development, 1987 - journals.biologists.com
This paper shows stage-and tissue-specific global demethylation and remethylation
occurring during embryonic development. The egg genome is strikingly undermethylated …
occurring during embryonic development. The egg genome is strikingly undermethylated …
[PDF][PDF] Active demethylation of the paternal genome in the mouse zygote
J Oswald, S Engemann, N Lane, W Mayer, A Olek… - Current Biology, 2000 - cell.com
DNA methylation is essential for the control of a number of biological mechanisms in
mammals [1]. Mammalian development is accompanied by two major waves of genome …
mammals [1]. Mammalian development is accompanied by two major waves of genome …
Methylation reprogramming and chromosomal aneuploidy in in vivo fertilized and cloned rabbit preimplantation embryos
W Shi, F Dirim, E Wolf, V Zakhartchenko… - Biology of …, 2004 - academic.oup.com
Active demethylation of the paternal genome but not of the maternal genome occurs in
fertilized mouse, rat, pig, and bovine zygotes. To study whether this early demethylation …
fertilized mouse, rat, pig, and bovine zygotes. To study whether this early demethylation …
Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line.
Methylation patterns of specific genes have been studied by polymerase chain reaction and
found to undergo dynamic changes in the germ line and early embryo. Some CpG sites are …
found to undergo dynamic changes in the germ line and early embryo. Some CpG sites are …
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