Efficacy and safety of nivolumab for malignant mesothelioma in the real world.

K Mikami, T Yokoi, R Takahashi, E Shibata, M Niki… - 2020 - ascopubs.org
9052 Background: Until recently, the standard treatment for advanced malignant pleural
mesothelioma (MPM) was only cisplatin plus pemetrexed. Nivolumab, an anti-programmed …

OA 02.02 Ipilimumab and nivolumab in the treatment of recurrent malignant pleural mesothelioma: a phase II study

M Disselhorst, E Harms, H Van Tinteren… - Journal of Thoracic …, 2017 - jto.org
Background There is an increasing interest in the use of IO therapy in Mesothelioma (MPM).
We previously reported on the effect of nivolumab (sa) in patients with recurrent MPM with a …

Management of advanced pleural mesothelioma—at the crossroads

AK Nowak, A Jackson, C Sidhu - JCO Oncology Practice, 2022 - ascopubs.org
The management of pleural mesothelioma has changed with the demonstration that first-line
checkpoint blockade therapy improves survival. This review covers issues of relevance to …

[HTML][HTML] Nivolumab immunotherapy in malignant mesothelioma: a case report highlighting a new opportunity for exceptional outcomes

RG Jones, F Karthik, A Dugar… - The American Journal …, 2018 - ncbi.nlm.nih.gov
Objective: Rare disease Background: Malignant pleural mesothelioma (MPM) is a highly
lethal cancer with a median survival of∼ 12 months even with aggressive intervention …

Advances in immunotherapy of malignant pleural mesothelioma

D Liao, Y Yu, Q Mei, Z Wang, X Li, Y Jia… - OncoTargets and …, 2021 - Taylor & Francis
Malignant pleural mesothelioma (MPM) represents the uncommon cancer originating from
pleural mesothelial cells, which is associated with dismal prognostic outcome. According to …

Nivolumab in pretreated pleural mesothelioma: Results from an observational real-world study of patients treated within the AIFA 5% Fund

L Cerbone, S Delfanti, S Crivellari… - Tumori …, 2024 - journals.sagepub.com
Background: Pleural mesothelioma is a rare cancer with a dismal prognosis and few
therapeutic options, especially in the pretreated setting. Immunotherapy with checkpoint …

[HTML][HTML] Final results of DIADEM, a phase II study to investigate the efficacy and safety of durvalumab in advanced pretreated malignant pleural mesothelioma

S Canova, GL Ceresoli, F Grosso, PA Zucali… - ESMO open, 2022 - Elsevier
Background Malignant pleural mesothelioma (MPM) is a cancer with a high mortality rate
and few therapeutic options. After platinum–pemetrexed combination, no further promising …

[HTML][HTML] Comparison of FDG-PET/CT and CT for evaluation of tumor response to nivolumab plus ipilimumab combination therapy and prognosis prediction in patients …

K Kitajima, K Kuribayashi, T Minami, H Yokoyama… - Oncotarget, 2024 - ncbi.nlm.nih.gov
Objectives: Results for malignant pleural mesothelioma (MPM) patients following first-line
treatment with nivolumab plus ipilimumab obtained with immunotherapy-modified PERCIST …

Durvalumab with first-line chemotherapy in previously untreated malignant pleural mesothelioma (DREAM): a multicentre, single-arm, phase 2 trial with a safety run-in

AK Nowak, WJ Lesterhuis, PS Kok, C Brown… - The Lancet …, 2020 - thelancet.com
Background There is a strong unmet need to improve systemic therapy in mesothelioma.
Chemotherapy with cisplatin and pemetrexed improves survival in malignant pleural …

Immune checkpoint inhibitors in malignant pleural mesothelioma: promises and challenges

GL Ceresoli, M Bonomi, MG Sauta - Expert Review of Anticancer …, 2016 - Taylor & Francis
Malignant pleural mesothelioma (MPM) is a tumor with a poor prognosis, whose incidence is
increasing worldwide due to widespread previous exposure to asbestos. Only few patients …