In solid tumors, the development of vasculature is, to some extent, slower than the
proliferation of the different types of cells that form the tissue, both cancer and stroma cells …

One of the key factors that correlates with poor survival of patients with pancreatic cancer is
the extent of hypoxic areas within the tumor tissue. The adaptation of pancreatic cancer cells …

Attributable to its late diagnosis, early metastasis, and poor prognosis, pancreatic cancer
remains one of the most lethal diseases worldwide. Unlike other solid tumors, pancreatic …

Pancreatic cancer (PC) remains one of the most extremely lethal malignancies worldwide
due to late diagnosis and early metastasis, with a 1-year overall survival rate of …

Intratumoral hypoxia is a common feature of solid tumors. Recent advances in cancer
biology indicate that hypoxia is not only a consequence of unrestrained tumor growth, but …

Pancreatic cancer is one of the common malignant tumors of the digestive system and is
known as the “king of cancers”. It is extremely difficult to diagnose at an early stage, the …

Pancreatic ductal adenocarcinoma remains one of the most lethal of all solid tumors with an
overall five-year survival rate of only 3–5%. Its aggressive biology and resistance to …

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal solid tumors with
an overall five-year survival rate of that has only just reached 10%. The tumor …

Pancreatic cancer (PC) is one of the deadliest malignancies. The high mortality rate of PC
largely results from delayed diagnosis and early metastasis. Therefore, identifying novel …

Hypoxia is a common phenomenon in most malignant tumors, especially in pancreatic
cancer (PC). Hypoxia is the result of unlimited tumor growth and plays an active role in …