This study was aimed to study the interaction between purified irisin and rivastigmine tartrate
(RT), a cholinesterase inhibitor used in Alzheimer's therapy. Irisin mainly promotes brown fat …

The prevalence of Alzheimer's disease (AD) has been a major health concern for a long
time. Despite recent progress, there is still a strong need to develop effective disease …

Alzheimer's disease (AD) is the leading cause of dementia in older adults, having a
significant global burden and increasing prevalence. Current treatments for AD only provide …

Irisin is a potential therapeutic agent to prevent or treat various metabolic-related disorders
and neurodegenerative diseases viz. Alzheimer's disease (AD). In this study, we have …

Alzheimer's disease (AD) is characterized by progressive memory dysfunction, oxidative
stress, and presence of senile plaques formed by amyloid beta (Aβ) accumulation in the …

Irisin is a clinically significant protein playing a valuable role in regulating various diseases.
Irisin attenuates synaptic and memory dysfunction, highlighting its importance in Alzheimer's …

Despite being one of the greatest global challenges for health and social care in the 21st
century, Alzheimer's disease (AD) lacks specific medicine. Irisin, an exercise-generated …

The beneficial effects of exercise on human brain function have been demonstrated in
previous studies. Myokines secreted by muscle have attracted increasing attention because …

A pathological hallmark of Alzheimer's disease (AD) is the deposition of amyloid-β (Aβ)
protein in the brain. Physical exercise has been shown to reduce Aβ burden in various AD …

Irisin is a hormone-like molecule mainly released by skeletal muscles in response to
exercise. Irisin induces browning of the white adipose tissue and has been shown to …