Epstein-Barr virus: the impact of scientific advances on clinical practice

H Williams, DH Crawford - Blood, 2006 - ashpublications.org
Epstein-Barr virus (EBV) is a tumorigenic herpes virus that infects and persists in B
lymphocytes in the majority of humans, generally without causing disease. However, in a …

[HTML][HTML] EBV-associated diseases: Current therapeutics and emerging technologies

S Chakravorty, B Afzali, M Kazemian - Frontiers in Immunology, 2022 - frontiersin.org
EBV is a prevalent virus, infecting> 90% of the world's population. This is an oncogenic virus
that causes~ 200,000 cancer-related deaths annually. It is, in addition, a significant …

Epstein-Barr virus: Biology and clinical disease

B Damania, SC Kenney, N Raab-Traub - Cell, 2022 - cell.com
Epstein-Barr virus (EBV) is a ubiquitous, oncogenic virus that is associated with a number of
different human malignancies as well as autoimmune disorders. The expression of EBV viral …

Epstein-Barr virus–associated epithelial and mesenchymal neoplasms

AT Deyrup - Human pathology, 2008 - Elsevier
Epstein-Barr virus (EBV) is a ubiquitous human pathogen that usually maintains a
harmonious relationship with its host. Rarely, this host-virus balance is perturbed, causing a …

Immune escape by Epstein–Barr virus associated malignancies

C Münz, A Moormann - Seminars in cancer biology, 2008 - Elsevier
Persistent Epstein–Barr virus (EBV) infection remains asymptomatic in the majority of virus
carriers, despite the potent growth transforming potential of this virus. The increased …

Epstein-Barr virus: an important vaccine target for cancer prevention

JI Cohen, AS Fauci, H Varmus, GJ Nabel - Science translational …, 2011 - science.org
Participants at the February 2011 meeting at the US National Institutes of Health on Epstein-
Barr virus (EBV) vaccine research recommend that future clinical trials have two goals …

Epstein–Barr virus infection and nasopharyngeal carcinoma

SW Tsao, CM Tsang, KW Lo - … Transactions of the …, 2017 - royalsocietypublishing.org
Epstein–Barr virus (EBV) is associated with multiple types of human cancer, including
lymphoid and epithelial cancers. The closest association with EBV infection is seen in …

Direct sequencing and characterization of a clinical isolate of Epstein-Barr virus from nasopharyngeal carcinoma tissue by using next-generation sequencing …

P Liu, X Fang, Z Feng, YM Guo, RJ Peng, T Liu… - Journal of …, 2011 - Am Soc Microbiol
ABSTRACT Epstein-Barr virus (EBV)-encoded molecules have been detected in the tumor
tissues of several cancers, including nasopharyngeal carcinoma (NPC), suggesting that …

[HTML][HTML] Integrative identification of Epstein–Barr virus–associated mutations and epigenetic alterations in gastric cancer

Q Liang, X Yao, S Tang, J Zhang, TO Yau, X Li… - Gastroenterology, 2014 - Elsevier
Background & Aims The mechanisms by which Epstein–Barr virus (EBV) contributes to the
development of gastric cancer are unclear. We investigated EBV-associated genomic and …

[HTML][HTML] The role of Epstein–Barr virus in nasopharyngeal carcinoma

ZY Su, PY Siak, CO Leong, SC Cheah - Frontiers in Microbiology, 2023 - frontiersin.org
Nasopharyngeal carcinoma (NPC) is a metastasis-prone malignancy closely associated
with the Epstein–Barr virus (EBV). Despite ubiquitous infection of EBV worldwide, NPC …