Several hundred carotenoid research studies have been published since 1996, when two
major intervention trials showed a lack of protective effect of β-carotene supplements against …

Background Carotenoids are thought to have anti-cancer properties, but findings from
population-based research have been inconsistent. Objective We aimed to conduct a …

The epidemiologic evidence that carotenoids are involved in cancer etiology is evaluated.
Low intake of vegetables and fruits and carotenoids is consistently associated with an …

Intervention trials with supplemental β-carotene have observed either no effect or a harmful
effect on lung cancer risk. Because food composition databases for specific carotenoids …

Based on extensive epidemiological observation, fruits and vegetables that are a rich source
of carotenoids are thought to provide health benefits by decreasing the risk of various …

Increased intake of vegetables, fruits, and carotenoids and elevated blood levels of β-
carotene are consistently associated with reduced risk of lung cancer in epidemiologic …

Smoking prevention and cessation remain the primary methods of reducing the incidence of
lung cancer. The limited success of efforts towards smoking cessation have led to increasing …

The conflicting evidence of the relation between β-carotene and lung cancer in humans
serves as a poignant case study with respect to what types of evidence are sufficient to …

Results from trials of beta-carotene supplementation indicate that it is harmless for an
apparently health group of individuals over a long-term period, but it can increase the risk of …

The IARC convened a Working Group of experts in December 1997 to evaluate the cancer-
preventive potential of carotenoids and to compile the second volume of the IARC …