Angiotensin-converting enzyme 2 (ACE2) receptor and SARS-CoV-2: potential therapeutic targeting
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a beta coronavirus that
uses the human angiotensin-converting enzyme 2 (ACE2) receptor as a point of entry. The …
uses the human angiotensin-converting enzyme 2 (ACE2) receptor as a point of entry. The …
Expression of ACE2 in airways: Implication for COVID‐19 risk and disease management in patients with chronic inflammatory respiratory diseases
Y Yao, H Wang, Z Liu - Clinical & Experimental Allergy, 2020 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by the novel severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has been a rising international cause of …
respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has been a rising international cause of …
ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs
IT Lee, T Nakayama, CT Wu, Y Goltsev, S Jiang… - Nature …, 2020 - nature.com
The coronavirus SARS-CoV-2 is the causative agent of the ongoing severe acute respiratory
disease pandemic COVID-19. Tissue and cellular tropism is one key to understanding the …
disease pandemic COVID-19. Tissue and cellular tropism is one key to understanding the …
The protein expression profile of ACE2 in human tissues
F Hikmet, L Méar, Å Edvinsson, P Micke… - Molecular systems …, 2020 - embopress.org
The novel SARS‐coronavirus 2 (SARS‐CoV‐2) poses a global challenge on healthcare and
society. For understanding the susceptibility for SARS‐CoV‐2 infection, the cell type‐specific …
society. For understanding the susceptibility for SARS‐CoV‐2 infection, the cell type‐specific …
SARS-CoV-2 Entry Receptor ACE2 Is Expressed on Very Small CD45− Precursors of Hematopoietic and Endothelial Cells and in Response to Virus Spike Protein …
MZ Ratajczak, K Bujko, A Ciechanowicz… - Stem cell reviews and …, 2021 - Springer
Abstract Angiotensin-converting enzyme 2 (ACE2) plays an important role as a member of
the renin–angiotensin–aldosterone system (RAAS) in regulating the conversion of …
the renin–angiotensin–aldosterone system (RAAS) in regulating the conversion of …
SARS-CoV-2 cellular entry is independent of the ACE2 cytoplasmic domain signaling
T Karthika, J Joseph, VRA Das, N Nair, P Charulekha… - Cells, 2021 - mdpi.com
Recently emerged severe acute respiratory syndrome coronavirus (SARS-CoV)-1 and-2
initiate virus infection by binding of their spike glycoprotein with the cell-surface receptor …
initiate virus infection by binding of their spike glycoprotein with the cell-surface receptor …
Insights on SARS-CoV-2 molecular interactions with the renin-angiotensin system
LB Costa, LG Perez, VA Palmeira… - Frontiers in Cell and …, 2020 - frontiersin.org
The emergence of SARS-CoV-2/human/Wuhan/X1/2019, a virus belonging to the species
Severe acute respiratory syndrome-related coronavirus, and the recognition of Coronavirus …
Severe acute respiratory syndrome-related coronavirus, and the recognition of Coronavirus …
Body localization of ACE-2: on the trail of the keyhole of SARS-CoV-2
F Salamanna, M Maglio, MP Landini, M Fini - Frontiers in medicine, 2020 - frontiersin.org
The explosion of the new coronavirus (SARS-CoV-2) pandemic has brought the role of the
angiotensin converting enzyme 2 (ACE2) back into the scientific limelight. Since SARS-CoV …
angiotensin converting enzyme 2 (ACE2) back into the scientific limelight. Since SARS-CoV …
Structural and functional basis of SARS-CoV-2 entry by using human ACE2
The recent emergence of a novel coronavirus (SARS-CoV-2) in China has caused
significant public health concerns. Recently, ACE2 was reported as an entry receptor for …
significant public health concerns. Recently, ACE2 was reported as an entry receptor for …
[HTML][HTML] Soluble ACE2 as a potential therapy for COVID-19
S Krishnamurthy, RF Lockey… - American Journal of …, 2021 - journals.physiology.org
Soluble angiotensin-converting enzyme 2 (sACE2) could be a therapeutic option to treat
coronavirus disease 2019 (COVID-19) infection. Severe acute respiratory syndrome …
coronavirus disease 2019 (COVID-19) infection. Severe acute respiratory syndrome …