Transformation of mammalian cells by human papillomavirus type 16 appears to require
binding of the viral E7 protein to the cellular retinoblastoma growth suppressor gene product …

The human papillomavirus E7 gene can transform murine fibroblasts and cooperate with
other viral oncogenes in transforming primary cell cultures. One biochemical property …

The ability of the high-risk and low-risk human papillomavirus E7 oncoproteins to disrupt
complexes of the retinoblastoma tumor suppressor protein pRB and the cellular transcription …

Human papillomaviruses (HPVs) are the etiological agents for genital warts and contribute
to the development of cervical cancer in humans. The HPV E7 gene product is expressed in …

The E7 proteins encoded by the human papillomaviruses (HPVs) associated with anogenital
lesions share significant amino acid sequence homology. The E7 proteins of these different …

Human papillomavirus type 16 E7 is considered to be a major viral oncoprotein playing an
important role (s) in cervical cancers. E7 protein was shown to bind to the protein product of …

The human papillomavirus E7 oncoprotein binds to the retinoblastoma (Rb) tumor
suppressor protein, and the binding to Rb correlates with the oncogenic potential of E7 …

The E7 oncoprotein from human Papillomavirus (HPV) mediates cell transformation in part
by binding to the human pRb tumor suppressor protein and E2F transcription factors …

Six derivatives of the human papillomavirus type 16 E7 gene were constructed, each of
which encoded a peptide at the amino terminus of the E7 protein capable of chelating metal …

The human papillomavirus type 16 (HPV-16) E7 gene encodes a multifunctional
oncoprotein that can subvert multiple cellular regulatory pathways. The best-known cellular …