Epigenetic regulation is the mechanism by which gene function is selectively activated or
inactivated in the cells. It provides higher-ordered and more specified genetic information …

The field of epigenetics has recently moved to the forefront of studies relating to diverse
processes such as transcriptional regulation, chromatin structure, genome integrity, and …

Cancer is a process driven by the accumulation of abnormalities in gene function. While
many of these changes are genetic, epigenetically mediated changes in gene expression …

Over three decades ago DNA methylation had been suggested to play a role in the
regulation of gene expression. This chapter reviews the development of this field of research …

Epigenetic modifications are heritable changes in gene expression not encoded by the DNA
sequence. In the past decade, great strides have been made in characterizing epigenetic …

DNA methylation is an epigenetic modification that is implicated in transcriptional silencing.
It is becoming increasingly clear that both correct levels and proper interpretation of DNA …

Although the field of genetics has grown by leaps and bounds within the last decade due to
the completion and availability of the human genome sequence, transcriptional regulation …

DNA methylation is a major epigenetic modification in the genomes of higher eukaryotes. In
vertebrates, DNA methylation occurs predominantly on the CpG dinucleotide, and …

DNA methylation is one of the most intensely studied epigenetic modifications in mammals.
In normal cells, it assures the proper regulation of gene expression and stable gene …

DNA methylation regulates many cellular processes, including embryonic development,
transcription, chromatin structure, X-chromosome inactivation, genomic imprinting and …