Background In 2013, the Declaration of Helsinki changed to mandate that all research
studies involving human subjects, rather than just clinical trials alone, must have a protocol …

Background Ensuring that published studies are of the highest methodological quality is a
critical step in plastic surgery's transition to a more evidence-based field. Reporting …

Background: Recent studies have identified a high incidence of discrepancy between
registered and published outcomes in registered medical and surgical randomized …

Background: Reproducible research—defined as the ability to replicate a study with its
published materials and procedures—is integral to ensuring the validity of published studies …

Background We recently conducted a systematic review of the methodological quality of
randomised controlled trials (RCTs) in plastic surgery. In accordance with convention, we …

Introduction The Declaration of Helsinki 2013 encourages the registration of all research
studies involving human participants. However, emphasis has been placed on prospective …

Abstract Background The Declaration of Helsinki has called for the registration of all
research studies involving human participants. Despite this, prior registries did not allow …

Abstract Background Randomized controlled trials (RCTs) are critical in developing new
therapeutic approaches. Historically, in plastic surgery, RCTs are uncommon as they make …

In 2011, Plastic and Reconstructive Surgery (PRS) implemented a level-of-evidence (LOE)
pyramid to bring attention to evidence-based medicine and to promote quality of research …

Transatlantic Innovations: New Frontiers in Plastic Surgery, involving both the United States
and Europe, were initiated in a combined kickoff meeting in February of 2009. 1 The …