Background: The benefits of chronic administration of estrogen to postmenopausal women
are well documented; however, the acute effects of exogenous estradiol on myocardium …

Recent studies in several animal models have suggested that estrogen, given for the short
term, may protect ischemic myocardium. Our objective was to test the effect of exogenous …

Abstract 17β-estradiol, administered acutely, protects ischemic myocardium in male rabbits.
In the present study we investigated the effect of short-term estrogen on myocardial infarct …

Although several studies have demonstrated that chronic exposure to estrogen appears to
be cardioprotective, acute circulatory effects of estrogen are largely unknown. Therefore, we …

BACKGROUND: Females demonstrate improved cardiac recovery after
ischemia/reperfusion injury compared with males. Attenuation of myocardial dysfunction with …

Menopausal status is a risk factor for coronary artery disease death, but the mechanism
underlying this association is uncertain. To test whether estrogen ameliorates the effects of …

Objective It has been reported that the progestin medroxyprogesterone acetate (MPA), but
not norethindrone acetate (NETA), inhibits the beneficial vascular effects of post …

Background Brief myocardial ischemia is associated with myocardial and coronary
endothelial dysfunction caused by oxygen free radicals released during reperfusion …

Objective: Results from recent clinical trials of estrogen and progestogen therapy (EPT)
suggest that some progestogens may interfere with the cardiovascular benefits of estrogen …

Previous studies demonstrated the protective effects of estrogen administration in models of
cardiovascular disease. However, there is a discrepancy between these data and those from …