Purpurascenines A–C, Azepino-Indole Alkaloids from Cortinarius purpurascens: Isolation, Biosynthesis, and Activity Studies on the 5-HT2A Receptor

YTH Lam, J Hoppe, QN Dang, A Porzel… - Journal of Natural …, 2023 - ACS Publications
Three previously undescribed azepino-indole alkaloids, named purpurascenines A–C (1–3),
together with the new-to-nature 7-hydroxytryptophan (4) as well as two known compounds …

Alkaloids from Eschscholzia californica and Their Capacity to Inhibit Binding of [3H]8-Hydroxy-2-(di-N-propylamino)tetralin to 5-HT1A Receptors in Vitro

S Gafner, BM Dietz, KL McPhail, IM Scott… - Journal of natural …, 2006 - ACS Publications
A 70% ethanol extract of California poppy (Eschscholzia californica) was able to bind to 5-
HT1A and 5-HT7 receptors at 100 μg/mL. The subsequent isolation procedure yielded the …

Two 5-HT1A Receptor-Interactive Tryptamine Derivatives from the Unripe Fruit of Evodia rutaecarpa

LL Yu, LK Ho, JF Liao, CF Chen - Journal of Natural Products, 1997 - ACS Publications
5-Methoxy-N, N-dimethyltryptamine (1) and N, N-dimethyltryptamine (2) isolated from the
dried, unripe fruit of Evodia rutaecarpa interacted with 5-HT1A receptors with K i values of 28 …

Uncarialins A–I, Monoterpenoid Indole Alkaloids from Uncaria rhynchophylla as Natural Agonists of the 5-HT1A Receptor

JH Liang, ZL Luan, XG Tian, WY Zhao… - Journal of natural …, 2019 - ACS Publications
Nine new monoterpenoid indole alkaloids, uncarialins A–I (1–9), were isolated from Uncaria
rhynchophylla as well as 14 known analogues (10–23). Their structures were determined by …

Serotonergic Activity-Guided Phytochemical Investigation of the Roots of Angelica sinensis

S Deng, SN Chen, P Yao, D Nikolic… - Journal of natural …, 2006 - ACS Publications
Serotonin receptor (5-HT7) binding assay-directed fractionation of a methanol extract of the
dried roots of Angelica sinensis led to the isolation and identification of 21 compounds …

6-Methoxy-N-methyl-1, 2, 3, 4-tetrahydro-β-carboline from Evodiae fructus

LL Yu, LK Ho, JF Liao, CF Chen - Planta medica, 1997 - thieme-connect.com
A receptor binding assay directed separation has led to the identification of a minor alkaloid
6-methoxy-N-methyl-1, 2, 3, 4-tetrahydro-β-carboline (1) from the Chinese herbal drug …

A New Structural Class of Bisindole Alkaloids from the Seeds of Catharanthus roseus: Vingramine and Methylvingramine

A Jossang, P Fodor, B Bodo - The Journal of Organic Chemistry, 1998 - ACS Publications
Two new bisindole alkaloids, vingramine (1) and methylvingramine (2), were isolated from
the seeds of Catharanthus roseus, Apocynaceae. The structures were determined by …

Bisanthraquinone glycosides of Hypericum perforatum with binding inhibition to CRH-1 receptors

A Wirz, U Simmen, J Heilmann, I Calis, B Meier… - Phytochemistry, 2000 - Elsevier
Four new bisanthraquinone glycosides, S-(+)-skyrin-6-O-β-glucopyranoside (1), R-(−)-skyrin-
6-O-β-glucopyranoside (2), S-(+)-skyrin-6-O-β-xylopyranoside (3) and S-(+)-skyrin-6-O-β-α …

(±)-Caryopterisines A and B, dimeric monoterpene alkaloids with unprecedented 6/5/5/5/6 pentacyclic rings scaffold from Caryopteris glutinosa

X Zhang, G Luo, Y Cao, D Mishig, M Lodonjav… - Bioorganic …, 2021 - Elsevier
Abstract (±)-Caryopterisines A (1) and B (2) featuring an unprecedented 6/5/5/5/6
pentacyclic rings system were isolated from Caryopteris glutinosa. The structures were …

Catharoseumine, a new monoterpenoid indole alkaloid possessing a peroxy bridge from Catharanthus roseus

L Wang, HP He, YT Di, Y Zhang, XJ Hao - Tetrahedron Letters, 2012 - Elsevier
Catharoseumine (1), a new monoterpenoid indole alkaloid possessing a unique peroxy
bridge moiety, was isolated from the whole plants of Catharanthus roseus. Its structure was …