Dominant negative mutator mutations in the mutS gene of Escherichia coli
TH Wu, MG Marinus - Journal of bacteriology, 1994 - Am Soc Microbiol
The MutS protein of Escherichia coli is part of the dam-directed MutHLS mismatch repair
pathway which rectifies replication errors and which prevents recombination between …
pathway which rectifies replication errors and which prevents recombination between …
[HTML][HTML] Deletion mutation analysis of the mutS gene inEscherichia coli
TH Wu, MG Marinus - Journal of Biological Chemistry, 1999 - ASBMB
The MutS protein is part of thedam-directed MutHLS mismatch repair pathway inEscherichia
coli. We have constructed deletion derivatives in the mutS gene, which retain the P-loop …
coli. We have constructed deletion derivatives in the mutS gene, which retain the P-loop …
The MutS C terminus is essential for mismatch repair activity in vivo
MA Calmann, A Nowosielska… - Journal of bacteriology, 2005 - Am Soc Microbiol
An Escherichia coli K-12 strain was constructed with a chromosomal deletion (mutS Δ 800)
in the mutS gene that produced the removal of the C-terminal 53 amino acids which are not …
in the mutS gene that produced the removal of the C-terminal 53 amino acids which are not …
Dominant Negative Mutator Mutations in the mutL Gene of Escherichia Coli
A Aronshtam, MG Marinus - Nucleic acids research, 1996 - academic.oup.com
The mutL gene product is part of the dam-directed mismatch repair system of Escherichia
coli but has no known enzymatic function. It forms a complex on heteroduplex DNA with the …
coli but has no known enzymatic function. It forms a complex on heteroduplex DNA with the …
Separation of mutation avoidance and antirecombination functions in an Escherichia coli mutS mutant
MA Calmann, A Nowosielska… - Nucleic acids …, 2005 - academic.oup.com
DNA mismatch repair in Escherichia coli has been shown to be involved in two distinct
processes: mutation avoidance, which removes potential mutations arising as replication …
processes: mutation avoidance, which removes potential mutations arising as replication …
Escherichia coli mutator mutD5 is defective in the mutHLS pathway of DNA mismatch repair.
RM Schaaper - Genetics, 1989 - academic.oup.com
We have previously reported that the Escherichia coli mutator strain mutD5 was defective in
the correction of bacteriophage M13mp2 heteroduplex DNA containing a TG mismatch …
the correction of bacteriophage M13mp2 heteroduplex DNA containing a TG mismatch …
The extreme mutator effect of Escherichia coli mutD5 results from saturation of mismatch repair by excessive DNA replication errors.
RM Schaaper, M Radman - The EMBO journal, 1989 - embopress.org
Escherichia coli mutator mutD5 is the most potent mutator known. The mutD5 mutation
resides in the dnaQ gene encoding the proofreading exonuclease of DNA polymerase III …
resides in the dnaQ gene encoding the proofreading exonuclease of DNA polymerase III …
Phylogenetic Evidence for Horizontal Transfer ofmutS Alleles among Naturally Occurring Escherichia coli Strains
EW Brown, JE LeClerc, B Li, WL Payne… - Journal of …, 2001 - Am Soc Microbiol
ABSTRACT mutS mutators accelerate the bacterial mutation rate 100-to 1,000-fold and relax
the barriers that normally restrict homeologous recombination. These mutators thus afford …
the barriers that normally restrict homeologous recombination. These mutators thus afford …
Mutation spectrum in Escherichia coli DNA mismatch repair deficient ( mutH ) strain
C Rewinski, MG Marinus - Nucleic acids research, 1987 - academic.oup.com
The Dam-directed post-replicatve mismatch repair system of Escherichia coli removes base
pair mismatches from DNA. The products of the mutH, mutL and mutS genes, among others …
pair mismatches from DNA. The products of the mutH, mutL and mutS genes, among others …
Mechanisms of mutagenesis in the Escherichia coli mutator mutD5: role of DNA mismatch repair.
RM Schaaper - Proceedings of the National Academy of …, 1988 - National Acad Sciences
To investigate the mechanisms of spontaneous mutation in the Escherichia coli mutD5
mutator strain, 502 mutations generated in this strain in the N-terminal part of the lacI gene …
mutator strain, 502 mutations generated in this strain in the N-terminal part of the lacI gene …