Gender-specific patterns of left ventricular and myocyte remodeling following myocardial infarction in mice deficient in the angiotensin II type 1a receptor
P Bridgman, MA Aronovitz, R Kakkar… - American Journal …, 2005 - journals.physiology.org
Left ventricular (LV) remodeling after myocardial infarction (MI) results from hypertrophy of
myocytes and activation of fibroblasts induced, in part, by ligand stimulation of the ANG II …
myocytes and activation of fibroblasts induced, in part, by ligand stimulation of the ANG II …
Angiotensin II type 2 receptor overexpression preserves left ventricular function after myocardial infarction
Z Yang, CM Bove, BA French, FH Epstein, SS Berr… - Circulation, 2002 - Am Heart Assoc
Background—The role of the angiotensin II type 2 receptor (AT2-R) in left ventricular (LV)
remodeling may depend on the underlying stimulus. We hypothesized that cardiac AT2-R …
remodeling may depend on the underlying stimulus. We hypothesized that cardiac AT2-R …
Angiotensin II type 1A receptor knockout mice display less left ventricular remodeling and improved survival after myocardial infarction
Background—Angiotensin II (Ang II) has been implicated in ventricular remodeling after
myocardial infarction (MI), which is an important determinant for prognosis after MI. The aim …
myocardial infarction (MI), which is an important determinant for prognosis after MI. The aim …
The angiotensin II type 2 receptor and improved adjacent region function post-MI
CM Bove, WD Gilson, CD Scott, FH Epstein… - Journal of …, 2005 - Taylor & Francis
Angiotensin II type 2 receptor (AT2-R) overexpression in the mouse heart preserves left
ventricular (LV) size and global LV function during post-MI remodeling. We hypothesized …
ventricular (LV) size and global LV function during post-MI remodeling. We hypothesized …
Interaction between AT1 and AT2 receptors during postinfarction left ventricular remodeling
S Voros, Z Yang, CM Bove, WD Gilson… - American Journal …, 2006 - journals.physiology.org
The relative contribution of the angiotensin II type 1 and 2 receptors (AT1-R and AT2-R) in
postmyocardial infarction (MI) remodeling remains incompletely understood. We studied five …
postmyocardial infarction (MI) remodeling remains incompletely understood. We studied five …
Angiotensin II type 1a receptor is involved in cell infiltration, cytokine production, and neovascularization in infarcted myocardium
H Toko, Y Zou, T Minamino, M Sakamoto… - … , and vascular biology, 2004 - Am Heart Assoc
Objective—Angiotensin II is critically involved in left ventricular remodeling after myocardial
infarction. Neovascularization has been thought to prevent the development of left …
infarction. Neovascularization has been thought to prevent the development of left …
IL-1β and TNF-α upregulate angiotensin II type 1 (AT1) receptors on cardiac fibroblasts and are associated with increased AT1 density in the post-MI heart
D Gurantz, RT Cowling, N Varki, E Frikovsky… - Journal of molecular and …, 2005 - Elsevier
Angiotensin (Ang) II plays an important role in post-myocardial infarction (MI) cardiac
remodeling. The Ang II type 1 (AT1) receptor which mediates most Ang II effects is …
remodeling. The Ang II type 1 (AT1) receptor which mediates most Ang II effects is …
Effects of angiotensin II receptor blockade versus angiotensin-converting-enzyme inhibition on ventricular remodelling following myocardial infarction in the mouse
RD Patten, MJ Aronovitz, M Einstein, M Lambert… - Clinical …, 2003 - portlandpress.com
Left ventricular (LV) remodelling following myocardial infarction (MI) is associated with
increased morbidity and mortality. Previous data suggest that angiotensin II (Ang II) plays a …
increased morbidity and mortality. Previous data suggest that angiotensin II (Ang II) plays a …
Angiotensin II type 1a receptor is involved in the occurrence of reperfusion arrhythmias
Background—A growing body of evidence has suggested that the renin-angiotensin system
plays an important role in the development of cardiac hypertrophy induced by hemodynamic …
plays an important role in the development of cardiac hypertrophy induced by hemodynamic …
TRANSITORY REDUCTION IN ANGIOTENSIN AT2 RECEPTOR EXPRESSION LEVELS IN POSTINFARCT REMODELLING IN RAT MYOCARDIUM
CJ Lax, AA Domenighetti, JM Pavia… - Clinical and …, 2004 - Wiley Online Library
Myocardial infarction (MI) poses a significant risk for sudden cardiac death. The
effectiveness of angiotensin‐converting enzyme (ACE) inhibitors and AT1 receptor blockade …
effectiveness of angiotensin‐converting enzyme (ACE) inhibitors and AT1 receptor blockade …