Background—Accumulating evidence has suggested that the cardiac renin-angiotensin
system is activated during the remodeling process after myocardial infarction (MI). Although …

ANG II has a clear role in development of cardiac hypertrophy, fibrosis, and dysfunction. It
has been difficult, however, to determine whether these actions are direct or consequences …

Background: It is well known that angiotensin converting enzyme (ACE) inhibitors and
angiotensin II type 1 (AT1) receptor blockers (ARBs) prevent left ventricular (LV) remodelling …

The aim of this study was to determine the role of the AT2 receptor (AT2R) in left ventricular
(LV) remodeling after myocardial infarction (MI). The left anterior descending arteries were …

Angiotensin II (AII) is a major determinant of arterial pressure and volume homeostasis,
mainly because of its vascular action via the AII type 1 receptor (AT1R). AII has also been …

Activation of AT1 (type 1 Ang) receptors stimulates cardiomyocyte hypertrophy in vitro.
Accordingly, it has been suggested that regression of cardiac hypertrophy associated with …

Objective: To study the effects of increased levels of myocardial angiotensin II type 1 (AT1)
receptor on microvascular growth following myocardial infarction (MI). Methods: MI was …

Background: Ang II (angiotensin II) type 1 (AT1) receptors play a critical role in
cardiovascular diseases such as hypertension. Rodents have 2 types of AT1 receptor (AT1A …

The angiotensin II (Ang II) type 1 (AT1) receptor mainly mediates the physiological and
pathological actions of Ang II, but recent studies have suggested that AT1 receptor …

To determine whether angiotensin II (Ang II) stimulation of adult ventricular myocytes in vitro
results in cellular hypertrophy, the changes in myocyte volume and protein content per cell …