Background Previous meta-analysis of outcome trials in hypertension have not specifically
focused on isolated systolic hypertension or they have explained treatment benefit mainly in …

The Systolic Hypertension in Europe (Syst-Eur) study investigated whether antihypertensive
treatment could decrease the risk of cardiovascular complications in elderly patients with …

Background Isolated systolic hypertension occurs in about 15% of people aged 60 years or
older. In 1989, the European Working Party on High Blood Pressure in the Elderly …

Risk of cardiovascular disease (CVD) increases incrementally with blood pressure, even
within the high-normal range. In the general population, 27% of CVD in women and 37% in …

Summary The Syst-Eur Trial is a concerted action of the European Community's Medical and
Health Research Programme. The trial is carried out in consultation with the World Health …

Isolated systolic hypertension is the most common hemodynamic form of hypertension in the
elderly. With a rapidly aging population, the prevalence of hypertension, particularly isolated …

Since 1971 several prospective randomized outcome trials on antihypertensive drug
treatment in elderly hypertensive patients have been published|| 1–11]. Four studies|| 1–3 …

Background To assess the impact of immediate versus delayed antihypertensive treatment
on the outcome of older patients with isolated systolic hypertension, we extended the double …

ContextThe Seventh Report of the Joint National Committee on Prevention, Detection,
Evaluation, and Treatment of High Blood Pressure emphasizes the importance of systolic …

Background In 1989, the European Working Party on High Blood Pressure in the Elderly
started the double-blind, placebo-controlled, Systolic Hypertension in Europe Trial to test the …