Transcription factors as readers and effectors of DNA methylation
Recent technological advances have made it possible to decode DNA methylomes at single-
base-pair resolution under various physiological conditions. Many aberrant or differentially …
base-pair resolution under various physiological conditions. Many aberrant or differentially …
DNA methylation and the regulation of gene transcription
JT Attwood, RL Yung, BC Richardson - Cellular and Molecular Life …, 2002 - Springer
The regulation of gene transcription is not simply dependent on the presence or absence of
DNA-binding transcription factors that turn genes on or off, but also involves processes …
DNA-binding transcription factors that turn genes on or off, but also involves processes …
Genomic DNA methylation: the mark and its mediators
Methylation of DNA at position five of the cytosine ring occurs at most CpG dinucleotides in
the mammalian genome and is essential for embryonic viability. With several of the key …
the mammalian genome and is essential for embryonic viability. With several of the key …
[HTML][HTML] Proteins that bind methylated DNA and human cancer: reading the wrong words
L Lopez-Serra, M Esteller - British journal of cancer, 2008 - nature.com
DNA methylation and the machinery involved in epigenetic regulation are key elements in
the maintenance of cellular homeostasis. Epigenetic mechanisms are involved in embryonic …
the maintenance of cellular homeostasis. Epigenetic mechanisms are involved in embryonic …
Dynamics and context-dependent roles of DNA methylation
C Ambrosi, M Manzo, T Baubec - Journal of molecular biology, 2017 - Elsevier
DNA methylation is one of the most extensively studied epigenetic marks. It is involved in
transcriptional gene silencing and plays important roles during mammalian development. Its …
transcriptional gene silencing and plays important roles during mammalian development. Its …
Intragenic DNA methylation in transcriptional regulation, normal differentiation and cancer
M Kulis, AC Queirós, R Beekman… - Biochimica et Biophysica …, 2013 - Elsevier
Ever since the discovery of DNA methylation at cytosine residues, the role of this so called
fifth base has been extensively studied and debated. Until recently, the majority of DNA …
fifth base has been extensively studied and debated. Until recently, the majority of DNA …
[HTML][HTML] Cross-talk between site-specific transcription factors and DNA methylation states
A Blattler, PJ Farnham - Journal of Biological Chemistry, 2013 - ASBMB
DNA methylation, which occurs predominantly at CpG dinucleotides, is a potent epigenetic
repressor of transcription. Because DNA methylation is reversible, there is much interest in …
repressor of transcription. Because DNA methylation is reversible, there is much interest in …
DNA methylation: old dog, new tricks?
CG Spruijt, M Vermeulen - Nature structural & molecular biology, 2014 - nature.com
DNA methylation is an epigenetic modification that is generally associated with repression of
transcription initiation at CpG-island promoters. Here we argue that, on the basis of recent …
transcription initiation at CpG-island promoters. Here we argue that, on the basis of recent …
[HTML][HTML] DNA methylation presents distinct binding sites for human transcription factors
DNA methylation, especially CpG methylation at promoter regions, has been generally
considered as a potent epigenetic modification that prohibits transcription factor (TF) …
considered as a potent epigenetic modification that prohibits transcription factor (TF) …
[PDF][PDF] Many paths to one goal? The proteins that recognize methylated DNA in eukaryotes
N Sasai, PA Defossez - International Journal of Developmental …, 2009 - researchgate.net
ABSTRACT DNA methylation is an epigenetically inherited chemical modification that is
associated with transcriptional silencing and is essential for mammalian development. The …
associated with transcriptional silencing and is essential for mammalian development. The …