Reperfusion of blood flow to an ischemic myocardium is imperative to survival; ironically, it
may also manifest several pathophysiological conditions. The most important of these are …

Background Brief myocardial ischemia is associated with myocardial and coronary
endothelial dysfunction caused by oxygen free radicals released during reperfusion …

The increase in cardiovascular disease and metabolic syndrome incidence following the
onset of menopause has highlighted the role of estrogen as a cardiometabolic protective …

Although several studies have demonstrated that chronic exposure to estrogen appears to
be cardioprotective, acute circulatory effects of estrogen are largely unknown. Therefore, we …

Cardiovascular diseases are the major cause of morbidity and mortality in the developed
world, and are increasing in significance in the developing world. Elucidation of the …

The purpose of this investigation was to determine if exogenous estrogen could attenuate
the ventricular arrhythmias caused by myocardial ischemia and reperfusion. Conjugated …

Background: The benefits of chronic administration of estrogen to postmenopausal women
are well documented; however, the acute effects of exogenous estradiol on myocardium …

The purpose of this study was to test whether the susceptibility of the heart to
ischemia/reperfusion injury is modulated by the chronic estrogen status, ie, increased with …

Aging and estrogen deficiency increase the risk for developing cardiovascular disease
(CVD). Oxidative stress has also been implicated in the pathophysiology of CVD and in …

Recent studies in several animal models have suggested that estrogen, given for the short
term, may protect ischemic myocardium. Our objective was to test the effect of exogenous …