Background: Abdominal aortic aneurysm (AAA) refers to localized dilation of abdominal
aorta. AAA is largely asymptomatic, but aneurysmal rupture results in a high mortality rate …

Background: Abdominal aortic aneurysm (AAA), a common disease involving the segmental
expansion and rupture of the aorta, has a high mortality rate. Therapeutic options for AAA …

Objective This review describes ongoing efforts to develop a medical therapy to limit
abdominal aortic aneurysm (AAA) growth. Methods Data from animal model studies, human …

Abdominal aortic aneurysm (AAA) is a local expansion of the abdominal aorta wall caused
by a complex multifactorial maladaptive vascular remodeling. Despite recent advances in …

Background Management of abdominal aortic aneurysms (AAAs) relies on surgical repair of
larger AAAs. Consequently medical interventions inhibiting AAA progression could greatly …

Objective: There are no current effective abdominal aortic aneurysm (AAA) drug therapies.
An important limitation of most preclinical studies is that they test the effect of drugs on AAA …

Background Pharmacotherapy may represent a potential means to limit the expansion rate
of abdominal aortic aneurysms (AAAs). Studies evaluating the efficacy of different …

Background Management of abdominal aortic aneurysms (AAAs) relies on surgical repair of
larger AAAs. Consequently medical interventions inhibiting AAA progression could greatly …

Abdominal aortic aneurysm (AAA) causes∼ 170 000 deaths annually worldwide. Most
guidelines recommend asymptomatic small AAAs (30 to< 50 mm in women; 30 to< 55 mm in …

Abdominal aortic aneurysm (AAA) rupture is a common cause of death in adults. Current
AAA treatment is by open surgical or endovascular aneurysm repair. Rodent model and …