Ca2+ signaling influences nearly every aspect of cellular life. Transient receptor potential
(TRP) ion channels have emerged as cellular sensors for thermal, chemical and mechanical …

The 28 mammalian members of the super-family of transient receptor potential (TRP)
channels are cation channels, mostly permeable to both monovalent and divalent cations …

Transient receptor potential (TRP) cation channels play diverse roles in cellular Ca2+
signaling. First, as Ca2+-permeable channels that respond to a variety of stimuli, TRP …

The 30+ members of the family of TRP channels are diverse in their physiological roles, yet
the mechanisms that regulate their gating may be conserved. In particular, all TRP channels …

Calcium ions (Ca2+) are particularly important in cellular homeostasis and activity. To elicit
physiologically relevant timing and spatial patterns of Ca2+ signaling, ion channels in the …

The selective exchange of ions across cellular membranes is a vital biological process.
Ca2+-mediated signaling is implicated in a broad array of physiological processes in cells …

There is a rapidly growing interest in the family of transient receptor potential (TRP)
channels because TRP channels are not only important for many sensory systems, but they …

Abstract Transient Receptor Potential (TRP) family mediate the influx of monovalent and/or
divalent cations into cells in response to environmental stimuli. Pharmacological or genetic …

Transient receptor potential (TRP) channels are transmembrane protein complexes that play
important roles in the physiology and pathophysiology of both the central nervous system …

Calcium (Ca2+) is an ubiquitous intracellular signal that is responsible for a plethora of
cellular processes including fertilization, secretion, contraction, neuronal signaling and …