Long-term exposure to environmental concentrations of the pharmaceutical ethynylestradiol causes reproductive failure in fish

JP Nash, DE Kime, LTM Van der Ven… - Environmental …, 2004 - ehp.niehs.nih.gov
Heightened concern over endocrine-disrupting chemicals is driven by the hypothesis that
they could reduce reproductive success and affect wildlife populations, but there is little …

Concentration- and Time-dependent Effects of the Synthetic Estrogen, 17α-ethinylestradiol, on Reproductive Capabilities of the Zebrafish, Danio rerio

C Schäfers, M Teigeler, A Wenzel… - Journal of Toxicology …, 2007 - Taylor & Francis
Partial or full life-cycle tests are needed to assess the potential of endocrine-disrupting
compounds (EDCs) to adversely affect development and reproduction of fish. Small fish …

Effects of ethynylestradiol on the reproductive physiology in zebrafish (Danio rerio): Time dependency and reversibility

K Van den Belt, PW Wester… - … and Chemistry: An …, 2002 - Wiley Online Library
Environmental pollution with natural or synthetic estrogens may pose a serious threat to
reproduction of wildlife species. This study describes the effects of 17‐α‐ethynylestradiol …

An environmental estrogen alters reproductive hierarchies, disrupting sexual selection in group-spawning fish

TS Coe, PB Hamilton, D Hodgson… - … science & technology, 2008 - ACS Publications
There is global concern regarding the potential impacts of endocrine-disrupting chemicals
(EDCs) on the health of wildlife and humans. Exposure to some estrogens, at concentrations …

Endocrine disrupting chemicals and sexual behaviors in fish–a critical review on effects and possible consequences

M Söffker, CR Tyler - Critical reviews in toxicology, 2012 - Taylor & Francis
Endocrine disrupting chemicals (EDCs) enter aquatic ecosystems through discharged
effluents, mainly from wastewater treatment works and diffuse run off from land, and affect a …

An environmental oestrogen disrupts fish population dynamics through direct and transgenerational effects on survival and fecundity

AR Schwindt, DL Winkelman, K Keteles… - Journal of applied …, 2014 - Wiley Online Library
Increased need for water and projected declines in precipitation due to climate change
could leave waterways increasingly dominated by wastewater effluent. Understanding how …

Sexual reprogramming and estrogenic sensitization in wild fish exposed to ethinylestradiol

A Lange, GC Paull, TS Coe, Y Katsu… - Environmental …, 2009 - ACS Publications
Globally, feminization responses in wild male freshwater fish are caused by exposure to
estrogenic chemicals, including natural and synthetic estrogens, contained in effluents from …

[HTML][HTML] Developmental exposure of zebrafish (Danio rerio) to 17α-ethinylestradiol affects non-reproductive behavior and fertility as adults, and increases anxiety in …

K Volkova, NR Caspillo, T Porseryd, S Hallgren… - Hormones and …, 2015 - Elsevier
Exposure to estrogenic endocrine disruptors (EDCs) during development affects fertility,
reproductive and non-reproductive behavior in mammals and fish. These effects can also be …

Disruption of zebrafish (Danio rerio) embryonic development after full life-cycle parental exposure to low levels of ethinylestradiol

J Soares, AM Coimbra, MA Reis-Henriques… - Aquatic Toxicology, 2009 - Elsevier
Exposure of fish to the synthetic estrogen ethinylestradiol (EE2) has been shown to induce a
large set of deleterious effects. In addition to the negative impact of EE2 in reproductive …

Reproductive Effects of Ethynylestradiol and 4t-Octylphenol on the Zebrafish (Danio rerio)

K Van den Belt, R Verheyen, H Witters - Archives of environmental …, 2001 - Springer
In this study, the impact of ethynylestradiol (EE2) and 4t-octylphenol (OP) on reproduction in
zebrafish (Danio rerio) was evaluated using spawning and fertilization success …