Abstract Background Polynitroxylated PEGylated hemoglobin (PNPH, aka SanFlow)
possesses superoxide dismutase/catalase mimetic activities that may directly protect the …

841, 2002. First published November 8, 2001; 10.1152/ajpheart. 00880.2001.—The
beneficial effect of hemodilution on cerebral blood flow (CBF) during focal cerebral ischemia …

During subarachnoid haemorrhage, a blood clot forms in the subarachnoid space releasing
extracellular haemoglobin (Hb), which causes oxidative damage and cell death in …

Background Hemodilution with diaspirin crosslinked hemoglobin (DCLHb) ameliorates
occlusive cerebral ischemia. However, subarachnoid hemoglobin has been implicated as a …

Background: Previously, we had shown that elevation of cerebral perfusion pressure, using
pressors, improved short-term outcomes after traumatic brain injury and hemorrhagic shock …

Objective: A prehospital trial in trauma patients has been proposed to evaluate Hemopure
(hemoglobin glutamer-250 [bovine], hemoglobin-based oxygen carrying compound [HBOC] …

Purpose Optimal management of hemoglobin (Hb) and red blood cell transfusion (RBCT) in
neurologic intensive care unit (NICU) patients has not been determined yet. Here we aimed …

Background Restoration of brain tissue perfusion is a determining factor in the neurological
evolution of patients with traumatic brain injury (TBI) and hemorrhagic shock (HS). In a …

Objective: Hemoglobin‐based oxygen carriers, such as HBOC‐201, offer several potential
advantages over conventional resuscitation solutions or banked blood in the acute treatment …

Objective: There are few data regarding anemia and transfusion after subarachnoid
hemorrhage (SAH). We addressed the hypothesis that higher hemoglobin (HGB) levels are …