After chronic spinal injury, motoneurons spontaneously develop two persistent inward
currents (PICs): a TTX-sensitive persistent sodium current (sodium PIC) and a nimodipine …

After chronic spinal cord injury motoneurons exhibit large plateau potentials (sustained
depolarizations triggered by brief inputs) that play a primary role in the development of …

Months after sacral spinal transection in rats (chronic spinal rats), motoneurons below the
injury exhibit large, low-threshold persistent inward currents (PICs), composed of persistent …

In the months after spinal cord transection, motoneurons in the rat spinal cord develop large
persistent inward currents (PICs) that are responsible for muscle spasticity. These PICs are …

In the months after spinal cord injury, motoneurons develop large voltage-dependent
persistent inward currents (PICs) that cause sustained reflexes and associated muscle …

We examined the modulation of persistent inward currents (PICs) by serotonin (5-HT) in
spinal motoneurons of normal and chronic spinal rats. PICs are composed of both a TTX …

In spinal motoneurons in an in vivo preparation, we investigated the relationship between a
fast persistent inward current located in or near the soma and the capacity of these cells to …

Spinal motoneurons, like many neurons, respond with repetitive spiking to sustained inputs.
The afterhyperpolarization (AHP) that follows each spike, however, decays relatively slowly …

Spinal motoneurons can exhibit bistable behavior, which consists of stable self-sustained
firing that is initiated by a brief excitatory input and terminated by brief inhibitory input. This …

Motoneurons in the spinal cord have intrinsic voltage-dependent persistent inward currents
(PICs; eg persistent calcium currents) that amplify synaptic inputs by three-to five-fold in …