Comparison of a Lateral Flow Assay and a Latex Agglutination Test for the Diagnosis of Cryptococcus Neoformans Infection

T Schub, J Forster, S Suerbaum, J Wagener… - Current microbiology, 2021 - Springer
Infections by the basidiomycete yeast Cryptococcus neoformans are life-threatening
diseases claiming more than 600,000 lives every year. The most common manifestation is …

Large-scale evaluation of the immuno-mycologics lateral flow and enzyme-linked immunoassays for detection of cryptococcal antigen in serum and cerebrospinal fluid

J Hansen, ES Slechta… - Clinical and Vaccine …, 2013 - Am Soc Microbiol
Cryptococcosis is a systemic infection caused by the pathogenic yeasts Cryptococcus
neoformans and C. gattii. Detection of cryptococcal capsular antigen (CrAg) in serum and …

False-negative serum cryptococcal antigen lateral flow immunoassay result for a patient with disseminated cryptococcal disease

Y Xu, W Xia, F Ni - Infection and Drug Resistance, 2020 - Taylor & Francis
Cryptococcus neoformans (C. neoformans) is an opportunistic fungal pathogen to humans,
which can be acquired from environmental sources. Its most important virulence factor is its …

Evaluation of a Cryptococcus capsular polysaccharide detection FungiXpert LFA (lateral flow assay) for the rapid diagnosis of Cryptococcosis

Y Liu, M Kang, SY Wu, LJ Wu, L He, YL Xiao… - Medical …, 2022 - academic.oup.com
Cryptococcus is an opportunistic pathogenic fungus and is the major cause of fungal
meningitis. The cryptococcal antigen (CrAg) lateral flow assay (LFA) is an …

Clinical utility of the cryptococcal antigen lateral flow assay in a diagnostic mycology laboratory

BJ McMullan, C Halliday, TC Sorrell, D Judd… - PLoS …, 2012 - journals.plos.org
Background Cryptococcus neoformans causes life-threatening meningitis. A recently
introduced lateral flow immunoassay (LFA) to detect cryptococcal antigen (CRAG) is …

Real-time polymerase chain reaction detection of Cryptococcus neoformans and Cryptococcus gattii in human samples

V Veron, S Simon, D Blanchet, C Aznar - Diagnostic microbiology and …, 2009 - Elsevier
We report a TaqMan® real-time polymerase chain reaction (PCR) protocol for diagnosing
cryptococcosis. Specificity was tested with 33 fungal strains. The 7 clinical samples found …

Pitfalls in Serological Diagnosis of Cryptococcus gattii Infections

K Tintelnot, F Hagen, CO Han, M Seibold… - Medical …, 2015 - academic.oup.com
The detection of cryptococcal antigen by latex agglutination tests (LATs), enzyme-linked
immunoassays (ELISA), or lateral flow assay (LFA) is an important tool for diagnosis of a …

Low cryptococcus antigen titers as determined by lateral flow assay should be interpreted cautiously in patients without prior diagnosis of cryptococcal infection

M Dubbels, D Granger, ES Theel - Journal of Clinical …, 2017 - Am Soc Microbiol
ABSTRACT Detection of Cryptococcus antigen (CrAg) is invaluable for establishing
cryptococcal disease. Multiple different methods for CrAg detection are available, including …

Molecular Identification of Cryptococcus neoformans Serotypes

A Enache-Angoulvant, J Chandenier… - Journal of clinical …, 2007 - Am Soc Microbiol
Cryptococcus neoformans is a fungal pathogen that causes life-threatening infections
primarily in immunocompromised hosts. Based on the genetic characteristics and serologic …

The cryptococcal antigen lateral flow assay: A point-of-care diagnostic at an opportune time

MW Tang, KV Clemons, DA Katzenstein… - Critical reviews in …, 2016 - Taylor & Francis
Cryptococcal meningitis is a devastating HIV-related opportunistic infection, affecting nearly
1 million individuals and causing over 500 000 deaths each year. The burden of disease is …