Pulmonary oxidative stress, inflammation and cancer: respirable particulate matter, fibrous dusts and ozone as major causes of lung carcinogenesis through reactive …

A Valavanidis, T Vlachogianni, K Fiotakis… - International journal of …, 2013 - mdpi.com
Reactive oxygen or nitrogen species (ROS, RNS) and oxidative stress in the respiratory
system increase the production of mediators of pulmonary inflammation and initiate or …

Oxidative stress mechanisms in the pathogenesis of environmental lung diseases

RK Thimmulappa, I Chattopadhyay… - Oxidative Stress in Lung …, 2020 - Springer
Globally, respiratory diseases are major cause of disability and mortality, and more
alarmingly, it disproportionately affects developing countries, which is largely attributed to …

Oxidative stress and air pollution: its impact on chronic respiratory diseases

MP Sierra-Vargas, JM Montero-Vargas… - International Journal of …, 2023 - mdpi.com
Redox regulation participates in the control of various aspects of metabolism. Reactive
oxygen and nitrogen species participate in many reactions under physiological conditions …

Inflammation and lung cancer: roles of reactive oxygen/nitrogen species

N Azad, Y Rojanasakul, V Vallyathan - Journal of Toxicology and …, 2008 - Taylor & Francis
The lung is a highly specialized organ that facilitates uptake of oxygen and release of
carbon dioxide. Due to its unique structure providing enormous surface area to outside …

Air pollution exposure—the (in) visible risk factor for respiratory diseases

GP Bălă, RM Râjnoveanu, E Tudorache… - … Science and Pollution …, 2021 - Springer
There is increasing interest in understanding the role of air pollution as one of the greatest
threats to human health worldwide. Nine of 10 individuals breathe air with polluted …

Oxidative stress and inflammation in the normal airways and blood of patients with lung cancer and COPD

E Barreiro, C Fermoselle, M Mateu-Jimenez… - Free Radical Biology …, 2013 - Elsevier
Respiratory conditions such as chronic obstructive pulmonary disease (COPD) are
associated with a greater risk for lung cancer (LC). Oxidative stress and inflammation are …

Oxidative stress in the lung–the essential paradox

LK Rogers, MJ Cismowski - Current opinion in toxicology, 2018 - Elsevier
As eukaryotic life evolved, so too did the need for a source of energy that meets the
requirements of complex organisms. Oxygen provides this vast potential energy source, but …

Airborne particulate matter and human health: toxicological assessment and importance of size and composition of particles for oxidative damage and carcinogenic …

A Valavanidis, K Fiotakis… - Journal of Environmental …, 2008 - Taylor & Francis
Air pollution has been considered a hazard to human health. In the past decades, many
studies highlighted the role of ambient airborne particulate matter (PM) as an important …

Overview of the mechanisms of oxidative stress: impact in inflammation of the airway diseases

GD Albano, RP Gagliardo, AM Montalbano, M Profita - Antioxidants, 2022 - mdpi.com
Inflammation of the human lung is mediated in response to different stimuli (eg, physical,
radioactive, infective, pro-allergenic or toxic) such as cigarette smoke and environmental …

Air pollution: A culprit of lung cancer

Y Xue, L Wang, Y Zhang, Y Zhao, Y Liu - Journal of hazardous materials, 2022 - Elsevier
Air pollution is a global health problem, especially in the context of rapid economic
development and the expansion of urbanization. Herein, we discuss the harmful effects of …