Autoimmune diseases are chronic immune diseases characterized by dysregulation of
immune system, which ultimately results in a disruption in self-antigen tolerance. Cumulative …

Nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs) are pattern-
recognition receptors similar to toll-like receptors (TLRs). While TLRs are transmembrane …

Nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs) are a family of
intracellular sensors that have key roles in innate immunity and inflammation. Whereas …

Innate immunity is a primary defense system against microbial infections. Innate immune
pattern recognition receptors (PRRs) play pivotal roles in detection of invading pathogens …

Nucleotide-binding and oligomerization domain NOD-like receptors (NLRs) are highly
conserved cytosolic pattern recognition receptors that perform critical functions in surveying …

NOD1 {nucleotide-binding oligomerization domain 1; NLRC [NOD-LRR (leucine-rich repeat)
family with CARD (caspase recruitment domain) 1]} and NOD2 (NLRC2) are among the …

Cytosolic NOD-like receptors (NLRs) have been associated with human diseases including
infections, cancer, and autoimmune and inflammatory disorders. These innate immune …

Dysregulation of nucleotide-binding oligomerization domains 1 and 2 (NOD1 and NOD2)
has been implicated in the pathology of various inflammatory disorders, rendering them and …

NOD-like receptors (NLRs) comprise a family of cytosolic proteins that have been implicated
as ancient cellular sentinels mediating protective immune responses elicited by intracellular …

Nucleotide binding oligomerization domain (NOD)-like receptors are cytoplasmic pattern-
recognition receptors that together with RIG-I-like receptor (retinoic acid-inducible gene 1) …