[HTML][HTML] DNA methylation profiling of embryonic stem cell differentiation into the three germ layers
T Isagawa, G Nagae, N Shiraki, T Fujita, N Sato… - PloS one, 2011 - journals.plos.org
Embryogenesis is tightly regulated by multiple levels of epigenetic regulation such as DNA
methylation, histone modification, and chromatin remodeling. DNA methylation patterns are …
methylation, histone modification, and chromatin remodeling. DNA methylation patterns are …
[HTML][HTML] Critical period of nonpromoter DNA methylation acquisition during prenatal male germ cell development
The prenatal period of germ cell development is a key time of epigenetic programming in the
male, a window of development that has been shown to be influenced by maternal factors …
male, a window of development that has been shown to be influenced by maternal factors …
DNA methylation dynamics during the mammalian life cycle
JA Hackett, MA Surani - … of the Royal Society B: Biological …, 2013 - royalsocietypublishing.org
DNA methylation is dynamically remodelled during the mammalian life cycle through distinct
phases of reprogramming and de novo methylation. These events enable the acquisition of …
phases of reprogramming and de novo methylation. These events enable the acquisition of …
DNA methylation in the preimplantation embryo: the differing stories of the mouse and sheep
LE Young, N Beaujean - Animal reproduction science, 2004 - Elsevier
In mammals, active demethylation of cytosine methylation in the sperm genome prior to
forming a functional zygotic nucleus is thought to be a function of the oocyte cytoplasm …
forming a functional zygotic nucleus is thought to be a function of the oocyte cytoplasm …
[HTML][HTML] DNA methylation, environmental exposures and early embryo development
M Breton-Larrivée, E Elder, S McGraw - Animal reproduction, 2019 - SciELO Brasil
The first crucial step in the developmental program occurs during pre-implantation, the time
after the oocyte has been fertilized and before the embryo implants in the uterus. This period …
after the oocyte has been fertilized and before the embryo implants in the uterus. This period …
[HTML][HTML] Dynamics of DNA methylation during early development of the preimplantation bovine embryo
There is species divergence in control of DNA methylation during preimplantation
development. The exact pattern of methylation in the bovine embryo has not been …
development. The exact pattern of methylation in the bovine embryo has not been …
The role of DNA methylation in genome-wide gene regulation during development
Although it is well known that DNA methylation serves to repress gene expression, precisely
how it functions during the process of development remains unclear. Here, we propose that …
how it functions during the process of development remains unclear. Here, we propose that …
[HTML][HTML] Active demethylation of the paternal genome in the mouse zygote
J Oswald, S Engemann, N Lane, W Mayer, A Olek… - Current Biology, 2000 - cell.com
DNA methylation is essential for the control of a number of biological mechanisms in
mammals [1]. Mammalian development is accompanied by two major waves of genome …
mammals [1]. Mammalian development is accompanied by two major waves of genome …
DNA methylation in mouse embryonic stem cells and development
Mammalian development is associated with considerable changes in global DNA
methylation levels at times of genomic reprogramming. Normal DNA methylation is essential …
methylation levels at times of genomic reprogramming. Normal DNA methylation is essential …
[PDF][PDF] Interplay between DNA methylation, histone modification and chromatin remodeling in stem cells and during development.
Genes constitute only a small proportion of the mammalian genome, the majority of which is
composed of non-genic repetitive elements including interspersed repeats and satellites. A …
composed of non-genic repetitive elements including interspersed repeats and satellites. A …