Effect of limited DNA methylation reprogramming in the normal sheep embryo on somatic cell nuclear transfer
N Beaujean, J Taylor, J Gardner, I Wilmut… - Biology of …, 2004 - academic.oup.com
Active demethylation of cytosine residues in the sperm genome before forming a functional
zygotic nucleus is thought to be an important function of the oocyte cytoplasm for …
zygotic nucleus is thought to be an important function of the oocyte cytoplasm for …
A role for DNA methylation in gastrulation and somite patterning
CC Martin, L Laforest, MA Akimenko, M Ekker - Developmental biology, 1999 - Elsevier
DNA methylation constitutes an important epigenetic factor in the control of genetic
information. In this study, we analyzed expression of the DNA methyltransferase gene and …
information. In this study, we analyzed expression of the DNA methyltransferase gene and …
DNA methylation reprogramming in medaka fish, a promising animal model for environmental epigenetics research
X Wang, RK Bhandari - Environmental Epigenetics, 2020 - academic.oup.com
DNA methylation is a major epigenetic modification that undergoes dramatic changes in two
epigenetic reprogramming windows during development: first in preimplantation embryos …
epigenetic reprogramming windows during development: first in preimplantation embryos …
[PDF][PDF] DNA methylation state is preserved in the sperm-derived pronucleus of the pig zygote
Y Jeong, S Yeo, J Park, D Koo, W Chang… - International Journal of …, 2007 - ijdb.ehu.es
ABSTRACT DNA methylation reprogramming (DMR) during preimplantation development
erases differentiation-associated, unessential epigenetic information accumulated during …
erases differentiation-associated, unessential epigenetic information accumulated during …
[HTML][HTML] Continuing primordial germ cell differentiation in the mouse embryo is a cell-intrinsic program sensitive to DNA methylation
DM Maatouk, JL Resnick - Developmental Biology, 2003 - Elsevier
The initial cohort of mammalian gametes is established by the proliferation of primordial
germ cells in the early embryo. Primordial germ cells first appear in extraembyronic tissues …
germ cells in the early embryo. Primordial germ cells first appear in extraembyronic tissues …
Genome-wide survey reveals dynamic widespread tissue-specific changes in DNA methylation during development
Background Changes in DNA methylation in the mammalian genome during development
are frequent events and play major roles regulating gene expression and other …
are frequent events and play major roles regulating gene expression and other …
[PDF][PDF] DNA methylation establishment during oocyte growth: mechanisms and significance
S Tomizawa, J Nowacka-Woszuk, G Kelsey - Int J Dev Biol, 2012 - babraham.ac.uk
ABSTRACT DNA methylation in the oocyte has a particular significance: it may contribute to
gene regulation in the oocyte and marks specific genes for activity in the embryo, as in the …
gene regulation in the oocyte and marks specific genes for activity in the embryo, as in the …
Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation
Background Uncovering mechanisms of epigenome evolution is an essential step towards
understanding the evolution of different cellular phenotypes. While studies have confirmed …
understanding the evolution of different cellular phenotypes. While studies have confirmed …
Dynamic alterations in the paternal epigenetic landscape following fertilization
TG Jenkins, DT Carrell - Frontiers in genetics, 2012 - frontiersin.org
Embryonic development is a complex and dynamic process with frequent changes in gene
expression, ultimately leading to cellular differentiation and commitment of various cell lines …
expression, ultimately leading to cellular differentiation and commitment of various cell lines …
Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes
CR Farthing, G Ficz, RK Ng, CF Chan, S Andrews… - PLoS …, 2008 - journals.plos.org
DNA methylation patterns are reprogrammed in primordial germ cells and in preimplantation
embryos by demethylation and subsequent de novo methylation. It has been suggested that …
embryos by demethylation and subsequent de novo methylation. It has been suggested that …