ABSTRACT A major role of the methyl-directed mismatch repair (MMR) system of
Escherichia coli is to repair postreplicative errors. In this report, we provide evidence that …

In Escherichia coli and related enteric bacteria, repair of base‐base mismatches is
performed by two overlapping biochemical processes, methyl‐directed mismatch repair …

DNA mismatch repair (MMR) repairs mispaired bases in DNA generated by replication
errors. MutS or MutS homologs recognize mispairs and coordinate with MutL or MutL …

How can the activities of differ-ent proteins that act at two distant sites on DNA be coupled?
In cis mechanisms, an intact DNA helix is required so that the protein molecules can slide …

The MutL, MutS, and MutH proteins mediate methyl-directed mismatch (MDM) repair and
help to maintain chromosome stability in Escherichia coli. We determined the amounts of the …

The DNA binding properties of the mismatch repair protein MutL and their importance in the
repair process have been controversial for nearly two decades. We have addressed this …

The MutS, MutH and MutL proteins mediate methyl-directed-mismatch (MDM) repair in
Escherichia coli and Salmonella typhimurium. These proteins have been developed into …

DNA mismatch repair (MMR) corrects replication errors in newly synthesized DNA. It also
has an antirecombination action on heteroduplexes that contain similar but not identical …

Two methods were used in an attempt to increase the efficiency and strand selectivity of
methyl-directed mismatch repair of bacteriophage λ heteroduplexes in E. coli. Previous …

DNA repair is essential for combatting the adverse effects of damage to the genome. One
example of base damage is O6-methylguanine (O6mG), which stably pairs with thymine …