Terpenic fraction of Pterodon pubescens inhibits nuclear factor kappa B and extracellular signal-regulated protein Kinase 1/2 activation and deregulates gene …

MF Pereira, T Martino, SR Dalmau, MC Paes… - … and alternative medicine, 2012 - Springer
Background Plant derived compounds have been shown to be important sources of several
anti-cancer agents. As cell cycle deregulation and tumor growth are intimately linked, the …

Terpenic subfraction of Pterodon pubescens induces apoptosis of K562 leukemic cells by modulating gene expression

MF Pereira, T Martino, SR Dalmau… - Oncology …, 2011 - spandidos-publications.com
Deregulation of cell proliferation and apoptosis is linked to malignant cell development.
Leukemia is the most frequent cancer in children, and plants are important sources for new …

Pterodon pubescens seed extract induces the cell cycle arrest of leukemic cells by deregulating cyclin D1 and E2 mRNA levels

MF Pereira, T de Almeida Simão… - Oncology …, 2010 - spandidos-publications.com
Plant-derived compounds are important sources of effective anti-cancer agents. Pterodon
pubescens is a native Brazilian plant popularly known for its anti-inflammatory and anti …

Anti-cancer activity of Psoralea fructus through the downregulation of cyclin D1 and CDK4 in human colorectal cancer cells

GH Park, JH Sung, HM Song, JB Jeong - BMC complementary and …, 2016 - Springer
Abstract Background Psoralea Fructus (PF), the dried and ripe fruit of Psoralea corylifolia
exhibits an anti-cancer activity. However, the molecular mechanisms by which PF inhibits …

Ethyl acetate extract of Antenoron Filiforme inhibits the proliferation of triple negative breast cancer cells via suppressing Skp2/p21 signaling axis

Y Liao, S Li, J An, X Yu, X Tan, Y Gui, Y Wang, L Huang… - Phytomedicine, 2023 - Elsevier
Background Triple negative breast cancer (TNBC) has the worst prognosis of the any breast
cancer subtype, and the efficient therapeutical treatment is extremely limited. Antenoron …

Flavonoids isolated from Citrus platymamma induced G2/M cell cycle arrest and apoptosis in A549 human lung cancer cells

A Nagappan, HJ Lee, VVG Saralamma… - Oncology …, 2016 - spandidos-publications.com
Citrus platymamma hort. ex Tanaka belongs to the Rutaceae family and is widely used in
folk medicines in Korea due to its anti‑proliferative, anti‑cancer, anti‑oxidant, anti …

Lupane triterpene derivatives improve antiproliferative effect on leukemia cells through apoptosis induction

LS Valencia-Chan, N Estrada-Alfaro, JJ Ceballos-Cruz… - Molecules, 2022 - mdpi.com
Leukemia is one of the most frequent types of cancer. No effective treatment currently exists,
driving a search for new compounds. Simple structural modifications were made to novel …

Phyllanthus Suppresses Prostate Cancer Cell, PC‐3, Proliferation and Induces Apoptosis through Multiple Signalling Pathways (MAPKs, PI3K/Akt, NFκB, and …

YQ Tang, IB Jaganath, R Manikam… - Evidence‐Based …, 2013 - Wiley Online Library
Phyllanthus is a traditional medicinal plant that has been found to have antihepatitis,
antibacterial, and anticancer properties. The present studies were to investigate the in vitro …

Pterostilbene induces cell cycle arrest and apoptosis in MOLT4 human leukemia cells

K Siedlecka-Kroplewska, A Jozwik… - Folia Histochemica …, 2012 - journals.viamedica.pl
Pterostilbene, a polyphenolic compound present in grapes and other fruits, has been
demonstrated to inhibit growth and induce apoptosis and autophagy in some cancer cell …

Antiproliferative activity of Pterodon pubescens Benth. seed oil and its active principle on human melanoma cells

CR Vieira, MF Marques, PR Soares, L Matuda… - Phytomedicine, 2008 - Elsevier
On a preliminary screening, relevant in vitro antiproliferative activity was observed to the
crude ethanolic extract of Pterodon pubescens seed oil against the human melanoma cell …