[HTML][HTML] Clinical update on head and neck cancer: molecular biology and ongoing challenges

E Alsahafi, K Begg, I Amelio, N Raulf, P Lucarelli… - Cell death & …, 2019 - nature.com
Head and neck squamous cell carcinomas (HNSCCs) are an aggressive, genetically
complex and difficult to treat group of cancers. In lieu of truly effective targeted therapies …

Head and neck cancer: Current challenges and future perspectives

GR Bhat, RG Hyole, J Li - Advances in Cancer Research, 2021 - Elsevier
Head and neck cancers are a heterogeneous, aggressive and genetically complex
collection of malignancies of the oral cavity, nasopharynx, oropharynx, hypopharynx, larynx …

Head and neck cancer: from anatomy to biology

P Bose, NT Brockton, JC Dort - International journal of cancer, 2013 - Wiley Online Library
The 20th century saw great advances in anatomy‐based (surgery and radiotherapy) and
chemotherapy approaches for treating head and neck squamous cell carcinoma (HNSCC) …

[HTML][HTML] Overview of current and future biologically based targeted therapies in head and neck squamous cell carcinoma

A Matta, R Ralhan - Head & neck oncology, 2009 - Springer
Recent advances in genomics, proteomics, bioinformatics and systems biology have
unraveled the complex aberrant signaling networks in cancer. The knowledge accrued has …

[HTML][HTML] Clinical update on cancer: molecular oncology of head and neck cancer

Y Suh, I Amelio, T Guerrero Urbano, M Tavassoli - Cell death & disease, 2014 - nature.com
Head and neck cancers encompass a heterogeneous group of tumours that, in general, are
biologically aggressive in nature. These cancers remain difficult to treat and treatment can …

[HTML][HTML] Molecular landscape of head and neck cancer and implications for therapy

CS Farah - Annals of Translational Medicine, 2021 - ncbi.nlm.nih.gov
Head and neck squamous cell carcinomas (HNSCC) arising from the oral cavity, pharynx,
and larynx constitute the 6 th most common human cancer. Human papillomavirus (HPV) …

The molecular landscape of head and neck cancer

CR Leemans, PJF Snijders, RH Brakenhoff - Nature Reviews Cancer, 2018 - nature.com
Head and neck squamous cell carcinomas (HNSCCs) arise in the mucosal linings of the
upper aerodigestive tract and are unexpectedly heterogeneous in nature. Classical risk …

Novel prognostic clinical factors and biomarkers for outcome prediction in head and neck cancer: a systematic review

V Budach, I Tinhofer - The Lancet Oncology, 2019 - thelancet.com
Current algorithms for the clinical management of patients with squamous cell carcinoma of
the head and neck (HNSCC) are based on a stage-dependent strategy where all patients at …

[HTML][HTML] Head and neck squamous cell carcinoma

DE Johnson, B Burtness, CR Leemans… - Nature reviews Disease …, 2020 - nature.com
Most head and neck cancers are derived from the mucosal epithelium in the oral cavity,
pharynx and larynx and are known collectively as head and neck squamous cell carcinoma …

Emerging biomarkers in head and neck cancer in the era of genomics

H Kang, A Kiess, CH Chung - Nature reviews Clinical oncology, 2015 - nature.com
Head and neck cancer (HNC) broadly includes carcinomas arising from the mucosal
epithelia of the head and neck region as well as various cell types of salivary glands and the …