Immunosenescence is described as a decline in the normal functioning of the immune
system associated with physiologic ageing. Immunosenescence contributes to reduced …

Immunosenescence is a process associated with aging that leads to dysregulation of cells of
innate and adaptive immunity, which may become dysfunctional. Consequently, older adults …

In the older adult, the benefits of vaccination to prevent infectious disease are limited, mainly
because of the adaptive immune system's inability to generate protective immunity. The age …

An age‐related decline in immune functions, referred to as immunosenescence, is partially
responsible for the increased prevalence and severity of infectious diseases, and the low …

The aging immune system demonstrates a reduced capacity to mount a robust immune
response (immunosenescence), thereby increasing the susceptibility to various infectious …

Understanding why we age and how that process can be delayed or reversed are topics that
have engaged both researchers and the general public [1]. From a scientific perspective …

Highlights•Immunosenescence leads to increased susceptibility to infection and decreased
vaccine response.•Heme-oxygenase gene expression may be an important element in age …

Immunosenescence, also known as immune aging, refers to the degeneration,
compensation, and reconstruction of the immune system with aging. Immune aging is an …

With increasing age, the ability of the adaptive immune system to respond to vaccines and to
protect from infection declines. In parallel, the production of inflammatory mediators …

Immunosenescence resulting in decreased ability to control infectious disease contributes to
morbidity and mortality not only in the very elderly, but in all likelihood already from middle …