A chlamydial plasmid-dependent secretion system for the delivery of virulence factors to the host cytosol
L Lei, C Yang, MJ Patton, M Smelkinson, D Dorward… - MBio, 2021 - Am Soc Microbiol
Chlamydia are obligate intracellular Gram-negative bacteria distinguished by a unique
developmental biology confined within a parasitophorous vacuole termed an inclusion. The …
developmental biology confined within a parasitophorous vacuole termed an inclusion. The …
Plasmid-mediated transformation tropism of chlamydial biovars
L Song, JH Carlson, B Zhou, K Virtaneva… - Pathogens and …, 2014 - academic.oup.com
Chlamydia trachomatis and C. muridarum are human and mouse pathogens, respectively,
which show high conservation of gene order and content. Both species contain a common …
which show high conservation of gene order and content. Both species contain a common …
Chlamydia trachomatis plasmid-encoded Pgp4 is a transcriptional regulator of virulence-associated genes
Chlamydia trachomatis causes chronic inflammatory diseases of the eye and genital tract
and has global medical importance. The chlamydial plasmid plays an important role in the …
and has global medical importance. The chlamydial plasmid plays an important role in the …
Chlamydial lytic exit from host cells is plasmid regulated
Chlamydia trachomatis is an obligate intracellular bacterium that is a globally important
human pathogen. The chlamydial plasmid is an attenuating virulence factor, but the …
human pathogen. The chlamydial plasmid is an attenuating virulence factor, but the …
Orchestration of the mammalian host cell glucose transporter proteins-1 and 3 by Chlamydia contributes to intracellular growth and infectivity
Chlamydia are gram-negative obligate intracellular bacteria that replicate within a discrete
cellular vacuole, called an inclusion. Although it is known that Chlamydia require essential …
cellular vacuole, called an inclusion. Although it is known that Chlamydia require essential …
Type III secretion in Chlamydia
EA Rucks - Microbiology and Molecular Biology Reviews, 2023 - Am Soc Microbiol
Type III secretion systems (T3SSs) are utilized by Gram-negative pathogens to enhance
their pathogenesis. This secretion system is associated with the delivery of effectors through …
their pathogenesis. This secretion system is associated with the delivery of effectors through …
The Chlamydial Plasmid-Encoded Protein pgp3 Is Secreted into the Cytosol of Chlamydia-Infected Cells
The chlamydial cryptic plasmid encodes eight putative open reading frames (ORFs),
designated pORF1 to-8. Antibodies raised against these ORF proteins were used to localize …
designated pORF1 to-8. Antibodies raised against these ORF proteins were used to localize …
Requirement of GrgA for Chlamydia infectious progeny production, optimal growth, and efficient plasmid maintenance
B Lu, Y Wang, W Wurihan, A Cheng, S Yeung… - Mbio, 2024 - Am Soc Microbiol
Chlamydia, an obligate intracellular bacterial pathogen, has a unique developmental cycle
involving the differentiation of invading elementary bodies (EBs) to noninfectious reticulate …
involving the differentiation of invading elementary bodies (EBs) to noninfectious reticulate …
Chlamydial plasmid-dependent pathogenicity
G Zhong - Trends in microbiology, 2017 - cell.com
Most Chlamydia species carry a 7.5 kb plasmid encoding eight open reading frames
conventionally called plasmid glycoproteins 1–8 or pGP1–8. Although the plasmid is not …
conventionally called plasmid glycoproteins 1–8 or pGP1–8. Although the plasmid is not …
Chlamydia trachomatis plasmid gene protein 3 is essential for the establishment of persistent infection and associated immunopathology
Chlamydia trachomatis is an obligate intracellular bacterial pathogen that causes blinding
trachoma and sexually transmitted disease afflicting hundreds of millions of people globally …
trachoma and sexually transmitted disease afflicting hundreds of millions of people globally …