The diverse functions of microRNAs in animal development and disease

WP Kloosterman, RHA Plasterk - Developmental cell, 2006 - cell.com
MicroRNAs (miRNAs) control gene expression by translational inhibition and destabilization
of mRNAs. While hundreds of miRNAs have been found, only a few have been studied in …

Posttranscriptional regulation of microRNA biogenesis in animals

H Siomi, MC Siomi - Molecular cell, 2010 - cell.com
MicroRNAs (miRNAs) control gene expression in animals, plants, and unicellular eukaryotes
by promoting degradation or repressing translation of target mRNAs. miRNA expression is …

[HTML][HTML] MicroRNA function in animal development

E Wienholds, RHA Plasterk - FEBS letters, 2005 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNA molecules that post-transcriptionally
regulate gene expression by base-pairing to mRNAs. Hundreds of miRNAs have been …

microRNA functions

N Bushati, SM Cohen - Annu. Rev. Cell Dev. Biol., 2007 - annualreviews.org
microRNAs (miRNAs) are small noncoding RNAs that play important roles in
posttranscriptional gene regulation. In animal cells, miRNAs regulate their targets by …

Functional aspects of animal microRNAs

AE Williams - Cellular and molecular life sciences, 2008 - Springer
MicroRNAs (miRNAs) are a recently discovered family of small regulatory molecules that
function by modulating protein production. There are approximately 500 known mammalian …

microRNA control of cell-cell signaling during development and disease

JW Hagen, EC Lai - Cell Cycle, 2008 - Taylor & Francis
MicroRNAs (miRNAs) are critical post-transcriptional regulators that may collectively control
a majority of animal genes. With thousands of miRNAs identified, a pressing challenge is …

[HTML][HTML] MicroRNAs: processing, maturation, target recognition and regulatory functions

GC Shukla, J Singh, S Barik - Molecular and cellular pharmacology, 2011 - ncbi.nlm.nih.gov
The remarkable discovery of small noncoding microRNAs (miRNAs) and their role in
posttranscriptional gene regulation have revealed another fine-tuning step in the expression …

MicroRNAs in mammalian development

CT Lee, T Risom, WM Strauss - Birth Defects Research Part C …, 2006 - Wiley Online Library
Abstract Development in mammals is a complex process requiring gene expression to be
spatially and temporally well‐regulated. Factors modulate gene functioning by controlling …

A developmental view of microRNA function

Y Zhao, D Srivastava - Trends in biochemical sciences, 2007 - cell.com
MicroRNAs (miRNAs) are genomically encoded small non-coding RNAs that regulate flow of
genetic information by controlling translation or stability of mRNAs. Recent recognition that …

MicroRNAs in development and disease

AE Erson, EM Petty - Clinical genetics, 2008 - Wiley Online Library
Since the discovery of microRNAs (miRNAs) in Caenorhabditis elegans, mounting evidence
illustrates the important regulatory roles for miRNAs in various developmental …